Evidence map›Paper›PMID 38001692›Full record

ArticleCancers2023

Long-Term Follow-Up of Patients with Conjunctival Lymphoma after Individualized Lens-Sparing Electron Radiotherapy: Results from a Longitudinal Study.

Christian Hoffmann, Toke Ringbaek, Anja Eckstein, Wolfgang Deya, Alina Santiago, Martin Heintz, Wolfgang Lübcke, Frank Indenkämpen, Wolfgang Sauerwein, Andrea Flühs and 13 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Conjunctival lymphoma: case report.Romanian journal of ophthalmology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Christian HoffmannDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0002-5776-439X
Toke RingbaekDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Anja EcksteinNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.
Wolfgang DeyaDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Alina SantiagoDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Martin HeintzDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Wolfgang LübckeDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Frank IndenkämpenDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Wolfgang SauerweinDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Andrea FlühsDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Claudia Le GuinNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.ORCID 0000-0002-6088-6929
Andreas HuettmannNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.ORCID 0000-0003-2230-3873
Julia von TresckowNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.
Sophia GörickeNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.
Cornelius DeuschlNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.ORCID 0000-0001-9262-7289
Sourour MoliaviDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Christoph PoettgenDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0002-9224-9318
Thomas GaulerDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Nika GuberinaDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Patricia JohanssonNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.ORCID 0000-0002-3265-8689
Nikolaos BechrakisNational Center for Tumor Diseases (NCT) West, Campus Essen, 45147 Essen, Germany.
Martin StuschkeDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.
Maja GuberinaDepartment of Radiotherapy, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0003-3218-0539
National Center for Tumor Diseases · DEEssen University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irradiation with electrons is the primary treatment regime for localized conjunctival low-grade lymphomas. However, radiation-induced cataracts are a major cause of treatment-related morbidity. This study investigates whether lens-sparing electron irradiation produces sufficient disease control rates while preventing cataract formation. All consecutive patients with strictly conjunctival, low-grade Ann Arbor stage IE lymphoma treated with superficial electron irradiation between 1999 and 2021 at our department were reviewed. A total of 56 patients with 65 treated eyes were enrolled with a median follow-up of 65 months. The median dose was 30.96 Gy. A lens-spearing technique featuring a hanging rod blocking the central beam axis was used in 89.2% of all cases. Cumulative incidences of 5- and 10-year infield recurrences were 4.3% and 14.6%, incidences of 5- and 10-year outfield progression were 10.4% and 13.4%. We used patients with involvement of retroorbital structures treated with whole-orbit photon irradiation without lens protection-of which we reported in a previous study-as a control group. The cumulative cataract incidence for patients treated with electrons and lens protection was significantly lower (

Indexed as

conjunctival lymphomaelectronslens sparingMALT lymphomasocular adnexal tumorsradiation cataractsradiotherapy

Identifiers

PMID38001692
PMCPMC10670077
OpenAlexW4388727605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.