Evidence map›Paper›PMID 38001606›Full record

ArticleCancers2023

Antiproliferative Modulation and Pro-Apoptotic Effect of BR2 Tumor-Penetrating Peptide Formulation 2-Aminoethyl Dihydrogen Phosphate in Triple-Negative Breast Cancer.

Laertty Garcia de Sousa Cabral, Cyntia Silva Oliveira, Katielle Albuquerque Freire, Monique Gonçalves Alves, Vani Xavier Oliveira, Jean-Luc Poyet, Durvanei Augusto Maria

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Laertty Garcia de Sousa CabralLaboratory of Development and Innovation, Butantan Institute, Sao Paulo 69310-000, Brazil.ORCID 0000-0002-4586-2945
Cyntia Silva OliveiraFederal University of Sao Paulo (UNIFESP), Sao Paulo 09913-030, Brazil.ORCID 0000-0003-2049-7627
Katielle Albuquerque FreireCenter for Natural and Human Sciences, Federal University of ABC, Santo Andre 09210-580, Brazil.
Monique Gonçalves AlvesLaboratory of Development and Innovation, Butantan Institute, Sao Paulo 69310-000, Brazil.ORCID 0000-0003-3199-5330
Vani Xavier OliveiraFederal University of Sao Paulo (UNIFESP), Sao Paulo 09913-030, Brazil.
Jean-Luc PoyetINSERM UMRS976, Institut De Recherche Saint-Louis, Hôpital Saint-Louis, 75010 Paris, France.ORCID 0000-0002-3747-255X
Durvanei Augusto MariaLaboratory of Development and Innovation, Butantan Institute, Sao Paulo 69310-000, Brazil.
Universidade de São Paulo · BRUniversidade Federal do ABC · BRInserm · FRUniversidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88882.328116/2019-01National Council for Scientific and Technological Development 305056/2019-0
6 · The paper itself

Abstract

Breast cancer is the most common cancer in women, the so-called "Triple-Negative Breast Cancer" (TNBC) subtype remaining the most challenging to treat, with low tumor-free survival and poor clinical evolution. Therefore, there is a clear medical need for innovative and more efficient treatment options for TNBC. The aim of the present study was to evaluate the potential therapeutic interest of the association of the tumor-penetrating BR2 peptide with monophosphoester 2-aminoethyl dihydrogen phosphate (2-AEH

Indexed as

monophosphoesternano therapypeptidetriple-negative breast cancer

Identifiers

PMID38001606
PMCPMC10670255
OpenAlexW4388526307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.