Evidence map›Paper›PMID 38001509›Full record

ArticleDiabetology & metabolic syndrome2023

Cost-effectiveness of continuous glucose monitoring with FreeStyle Libre

Luciana Bahia, Karla F Mello, Lívia Lovato Pires Lemos, Naiane Lima Costa, Eduardo Mulinari, Domingos A Malerbi

Abstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Advances in Continuous Glucose Monitoring: Clinical Applications.Endocrinology and metabolism (Seoul, Korea) · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Impact of the FreeStyle Libre 2Diagnostics (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luciana BahiaBrazilian Diabetes Society, São Paulo, Brazil. lucianabahia@gmail.com.ORCID http://orcid.org/0000-0001-6433-5967
Karla F MelloBrazilian Diabetes Society, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0096-2325
Lívia Lovato Pires LemosIQVIA, Real World Insights, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-8921-515X
Naiane Lima CostaIQVIA, Real World Insights, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6675-2668
Eduardo MulinariIQVIA, Real World Insights, São Paulo, Brazil.ORCID http://orcid.org/0009-0006-6447-7512
Domingos A MalerbiBrazilian Diabetes Society, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7802-5983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypoglycemia is a barrier to optimal glucose control in the treatment of both type 1 (T1DM) and type 2 diabetes mellitus (T2DM). Blood glucose monitoring is essential in diabetes management. Inappropriate glucose management is associated with high mortality and morbidity. FreeStyle Libre

methodsA decision-tree model was developed to compare the cost-effectiveness ratio between FSL and conventional SMBG from the perspective of the Brazilian Public Healthcare System (SUS). The model captures the cumulative rates of acute complications such as severe hypoglicemia and diabetic ketoacidosis, per-event costs, and quality-adjusted life-years (QALYs) gained over a 1-year time horizon in adult and pediatric patients (≥ 4 years old) with T1DM or T2DM. Inputs from the Brazilian health databases, clinical trials, and real-world data were used in the study.

resultsThe results demonstrated that, regarding solely severe hypoglicemia and diabetic ketoacidosis events, T1DM have a QALY difference of 0.276, a cost difference of R$ 7.255, and an ICER of R$ 26,267.69 per QALY gained for CGM with FSL, when compared to conventional SMBG. T2DM results demonstrated equally a QALY difference of 0.184, a cost difference of R$ 7290, and an ICER of R$ 39,692.67 per QALY gained, in favour of CGM with FSL.

conclusionOur findings demonstrated that FSL is cost-effective in T1DM and T2DM for acute diabetic complications, from a SUS perspective. CGM with FSL can promote safe, convenient, and cost-effective glucose monitoring, therefore contributing to the improvement of the incidence of complications and quality of life.

Indexed as

Cost-effectivenessGlucose monitoringType 1 Diabetes mellitusType 2 Diabetes mellitus

Identifiers

PMID38001509
PMCPMC10675900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.