Evidence map›Paper›PMID 38001379›Full record

ArticleNature genetics2023

Age-associated transcriptional stress due to accelerated elongation and increased stalling of RNAPII.

Antonios Papadakis, Akos Gyenis, Joris Pothof, Jan H J Hoeijmakers, Argyris Papantonis, Andreas Beyer

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Nature genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Gene regulatory networks in disease and ageing.Nature reviews. Nephrology · 2024
    Review
  8. DNA Damage and Parkinson's Disease.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonios PapadakisCluster of Excellence on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Akos GyenisDepartment of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.
Joris PothofDepartment of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-3536-3162
Jan H J HoeijmakersDepartment of Molecular Genetics, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0003-3526-7795
Argyris PapantonisInstitute of Pathology, University Medical Centre Göttingen, Göttingen, Germany.ORCID 0000-0001-7551-1073
Andreas BeyerCluster of Excellence on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany. andreas.beyer@uni-koeln.de.ORCID 0000-0002-3891-2123

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) CECAD, EXC 2030-390661388Deutsche Forschungsgemeinschaft (German Research Foundation) FOR 5504 project 496650118Deutsche Forschungsgemeinschaft (German Research Foundation) SFB1565 project INST186/1479-1EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) Advanced Grant Dam2AgeEC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) EU ITN Address (GA-316390)U.S. Department of Health & Human Services | National Institutes of Health (NIH) P01 AG017242; DNA repair, mutations and cell agingU.S. Department of Health & Human Services | National Institutes of Health (NIH) PO1 AG017242
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38001379

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.