Evidence map›Paper›PMID 38001361›Full record

ArticleScientific reports2023

Wall thickness analysis method for judging the degree of lower extremity long bone healing.

Ying Li, Zhiwei Yang, Liangcheng Tong, Junsheng Yang, Jianling Wang, Yaoke Wen

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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ying Li *Department of Orthopedics, Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu, China.
Zhiwei Yang *Department of Orthopedics, Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu, China.
Liangcheng Tong *Department of Orthopedics, Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu, China.
Junsheng YangDepartment of Orthopedics, Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu, China.
Jianling WangDepartment of Orthopedics, Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu, China.
Yaoke WenSchool of Mechanical Engineering, Nanjing University of Science and Technology, No. 200 Xiaolingwei, Nanjing, 210094, Jiangsu, China. dbkj454@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the possibility of judging the degree of bone healing by wall thickness analysis provide reference for quantitative analysis of bone healing. Patients with lower limb fracture from April 2014 to October 2019 were recruited and divided into bone healing (group A), poor bone healing (group B), and nonunion (group C). Models were built in Mimics 20.0 with DICOM 3.0 data obtained from patient's CT. Three-dimensional geometric models of unaffected limb and affected limb after simulated removal of internal fixation were established, corresponding to basic phase and simulated phase, respectively. Wall thickness analysis was performed to obtain median wall thickness after meshing. R2 (median wall thickness ratio), R4 (CT value ratio), and R5 (healing index ratio) were obtained by calculating the ratio of each value in simulated phase to that in basic phase. Receiver operating characteristic curve analysis was used to evaluate the ability of Wall Thickness Analysis to indicate fracture healing. 112 CT scans of 79 patients were included in the study. The frequency of categorization in groups A, B, and C was 49, 37 and 26, respectively. The median R2 in groups A, B, and C was 0.91, 0.80, and 0.67, respectively (group A > group B > group C, all P < 0.05). The best cutoff point for R2 in predicting bone healing was 0.84, and predicting bone nonunion was 0.74. The Wall Thickness Analysis can be used to quantitatively evaluate fracture healing state, with median wall thickness ratio as a more intuitive and reliable judgment index.

Indexed as

Bones of Lower ExtremityFractures, BoneFracture Fixation, InternalFracture HealingHumansLower ExtremityRetrospective StudiesTreatment Outcome

Identifiers

PMID38001361
PMCPMC10673992

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