ArticleNature communications2023
Epidemiology, mortality, and health service use of local-level multimorbidity patterns in South Spain.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- A systematic review and meta-analysis of disease clusters in multimorbidity.Nature communications · 2025Pooled it
- Sex-specific multimorbidity clusters and all-cause mortality among community-dwelling older adults: findings from the ASPREE cohort.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- The Role of Advanced Practice Nurses in the Care of Multimorbid and Complex Chronically Ill Young and Middle-Aged Adults in Hospital Settings-Perspectives on Experience of APNs: A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- The effect of nurse care management on multimorbid patients' hospital utilization: a comparative-controlled trial and an exploratory cohort study.Nature communications · 2026Article
- Training needs and curricular priorities for managing multimorbidity in Spanish primary care: findings from a national exploratory online survey.BMC primary care · 2026Article
- Multimorbidity, health service use, and health insurance by socioeconomic groups in 31 countries: A multi-cohort study.PLoS medicine · 2026Article
- The structural roots of multimorbidity: social inequalities, health disparities, and systemic challenges in Southern Spain.International journal for equity in health · 2026Article
- Paths to multimorbidity: a longitudinal perspective on disease accumulation in Catalonia, Spain.European journal of public health · 2026Article
- Longitudinal pattern of multimorbidity in older adult population: latent transition analysis in 34 countries.American journal of epidemiology · 2026Article
- Multimorbidity trends in Catalonia, 2010-21: a population-based cohort study.International journal of epidemiology · 2026Article
- Multimorbidity quantification from the perspective of precision management: challenges and strategies.Annals of medicine · 2025Review
- Dynamics of multimorbidity patterns in older population across socioeconomic areas.Communications medicine · 2025Article
- Individual-level transitions between chronic disease multimorbidity clusters and the risk of five-year mortality in longitudinal cohort of Chinese middle-aged and older adults.Aging clinical and experimental research · 2025Article
- Prospective association between plasma amino acids and three Multimorbidity patterns in older adults.Scientific reports · 2025Article
- Development and evaluation of an integrated multispecialty clinic for people with multiple long-term conditions.Future healthcare journal · 2025Article
- Uncovering bridging diseases in complex multimorbidity pathways: A network science approach.PloS one · 2025Article
- Associations between sleep changes and multimorbidity patterns in middle-aged and older Chinese adults.Frontiers in public health · 2025Article
- Sex- and age-specific multimorbidity networks in middle-aged inpatients: a network-based comparative study between China and the United Kingdom.Innovation in aging · 2025Article
- Article
- Pharmacist-Led Interventions to Improve Medication Adherence Among Patients with Multimorbidity: A Scoping Review.Patient preference and adherence · 2025Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimorbidity -understood as the occurrence of chronic diseases together- represents a major challenge for healthcare systems due to its impact on disability, quality of life, increased use of services and mortality. However, despite the global need to address this health problem, evidence is still needed to advance our understanding of its clinical and social implications. Our study aims to characterise multimorbidity patterns in a dataset of 1,375,068 patients residing in southern Spain. Combining LCA techniques and geographic information, together with service use, mortality, and socioeconomic data, 25 chronicity profiles were identified and subsequently characterised by sex and age. The present study has led us to several findings that take a step forward in this field of knowledge. Specifically, we contribute to the identification of an extensive range of at-risk groups. Moreover, our study reveals that the complexity of multimorbidity patterns escalates at a faster rate and is associated with a poorer prognosis in local areas characterised by lower socioeconomic status. These results emphasize the persistence of social inequalities in multimorbidity, highlighting the need for targeted interventions to mitigate the impact on patients' quality of life, healthcare utilisation, and mortality rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.