Evidence map›Paper›PMID 38000841›Full record

ReviewNeurosurgery clinics of North America2024

Epilepsy Surgery for Cognitive Improvement in Epileptic Encephalopathy.

John R McLaren, Kristopher T Kahle, R Mark Richardson, Catherine J Chu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neurosurgery clinics of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John R McLarenDepartment of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School.
Kristopher T KahleHarvard Medical School; Department of Neurosurgery, Massachusetts General Hospital, 55 Fruit Street, Wang Building Room 333, Boston, MA 02114, USA.
R Mark RichardsonHarvard Medical School; Department of Neurosurgery, Massachusetts General Hospital, 55 Fruit Street, Their Building, 4th Floor, Boston, MA 02114, USA.
Catherine J ChuDepartment of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School. Electronic address: cjchu@mgh.harvard.edu.

Funding

Focal Thalamocortical Circuit Dysfunction Mediates Motor and Cognitive Deficits in Developmental EpilepsyR01NS115868 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CHU, CATHERINE J · 2020 to 2024
$3.4M
NINDS NIH HHS R01 NS115868
6 · The paper itself

Abstract

Epileptic encephalopathies are defined by the presence of frequent epileptiform activity that causes neurodevelopmental slowing or regression. Here, we review evidence that epilepsy surgery improves neurodevelopment in children with epileptic encephalopathies. We describe an example patient with epileptic encephalopathy without drug refractory seizures, who underwent successful diagnostic and therapeutic surgeries. In patients with epileptic encephalopathy, cognitive improvement alone is a sufficient indication to recommend surgical intervention in experienced centers.

Indexed as

EpilepsyChildCognitionElectroencephalographyHumansCase reportCSWSDevelopmental epileptic encephalopathyESESInterictal localizationNeurodevelopmentOutcomePediatric epilepsy surgery

Identifiers

PMID38000841
PMCPMC11384968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.