Evidence map›Paper›PMID 38000815›Full record

ArticleBMJ open2023

Association of serum potassium level with dietary potassium intake in Chinese older adults: a multicentre, cross-sectional survey.

Yifang Yuan, Aoming Jin, Ming-Hui Zhao, Hongxia Wang, Xiangxian Feng, Qianku Qiao, Ruijuan Zhang, Runlin Gao, Yangfeng Wu

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03290716 (Diet, Exercise and Cardiovascular Health - Effect of Salt Substitute and Stepwise Salt Supply Control in Reducing Blood Pressure in the Elderly in Nursing Homes in China), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03290716 nacompletednot on this map

Diet, Exercise and Cardiovascular Health - Effect of Salt Substitute and Stepwise Salt Supply Control in Reducing Blood Pressure in the Elderly in Nursing Homes in China: a Factorial Cluster-randomized Controlled Trial

TypeinterventionalSponsorPeking UniversityRan2017 to 2021Enrolled1,612ConditionsBlood PressureArmsSS, SSSC
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Potassium and the kidney.Nature reviews. Nephrology · 2026
    Review
  2. Article
  3. Article
  4. Role of dietary potassium and salt substitution in the prevention and management of hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yifang YuanPeking University Clinical Research Center, Peking University Health Science Center, Beijing, China.ORCID 0000-0002-3171-9179
Aoming JinPeking University First Hospital, Beijing, China.ORCID 0000-0002-7221-5444
Ming-Hui ZhaoRenal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
Hongxia WangHohhot Center for Disease Control and Prevention, Inner Mongolia, China.
Xiangxian FengChangzhi Medical College, Changzhi, China.
Qianku QiaoYangcheng Ophthalmic Hospital, Jincheng, Shanxi, China.
Ruijuan ZhangXian Jiaotong University, Xi'an, Shaanxi, China.
Runlin GaoFu Wai Hospital, National Center for Cardiovascular Diseases, Beijing, China.
Yangfeng WuPeking University First Hospital, Beijing, China wuyf@bjmu.edu.cn.ORCID 0000-0002-4451-1932
Peking University · CNChangzhi Medical College · CNFu Wai Hospital · CNInner Mongolia Comprehensive Disease Prevention and Control Center · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEvidence linking dietary potassium and serum potassium is virtually scarce and inconclusive. The aim of the study was to investigate the association between serum potassium level and potassium intake measured by 24-hour urine. We also explored whether the association differed across health conditions.

designA cross-sectional study conducted from September 2017 to March 2018.

setting48 residential elderly care facilities in northern China.

participantsParticipants aged 55 years and older and with both serum potassium and 24-hour urinary potassium measured were classified as having a low (apparently healthy), moderate (with ≥1 health condition but normal renal function) and high (with ≥1 health condition and abnormal renal function) risk of hyperkalaemia. EXPOSURE: Potassium intake is measured by 24-hour urinary potassium. OUTCOMES: Serum potassium in association with potassium intake after adjustment for age, sex, region and accounting for the cluster effect.

resultsOf 962 eligible participants (mean age 69.1 years, 86.8% men), 17.3% were at low risk, 48.4% at moderate risk and 34.3% at high risk of hyperkalaemia. Serum potassium was weakly associated with 24-hour urinary potassium among individuals with moderate (adjusted β=0.0040/L; p=0.017) and high (adjusted β=0.0078/L; p=0.003) but not low (adjusted β=0.0018/L; p=0.311) risk of hyperkalaemia.

conclusionsA weak association between dietary potassium intake and serum potassium level existed only among individuals with impaired renal function or other health conditions but not among apparently healthy individuals. The results imply that increasing dietary potassium intake may slightly increase the risk of hyperkalaemia but may also decrease the risk of hypokalaemia in unhealthy individuals, both of which have important health concerns. TRIAL REGISTRATION NUMBER: NCT03290716; Post-results.

Indexed as

HyperkalemiaAgedCross-Sectional StudiesEast Asian PeopleFemaleHumansMalePotassiumPotassium, DietaryPotassiumPotassium, DietaryAdult nephrologyBlood PressureNUTRITION & DIETETICS

Identifiers

PMID38000815
PMCPMC10679980
OpenAlexW4388980365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.