Evidence map›Paper›PMID 38000696›Full record

ArticleThe Journal of allergy and clinical immunology2024

Asthma morbidity measures across Black ethnic subgroups.

Leah Ishmael, Andrea Apter, Paula J Busse, Rafael Calderon-Candelario, Jennifer K Carroll, Thomas Casale, Juan C Celedón, Rubin Cohen, Tamera Coyne-Beasley, Jing Cui and 15 more

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Migration, educational, and asthma mortality disparities in the United States.The journal of allergy and clinical immunology. In practice · 2025
    Article
  3. Racial/ethnic discrimination and racial trauma: Concurrent evaluation among Black adults who smoke in the United States.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 16 institutions in 2 countries.

Leah IshmaelDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.
Andrea ApterDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
Paula J BusseDivision of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY.
Rafael Calderon-CandelarioDivision of Pulmonary and Critical Care, Miami VA Healthcare System, Miami, Fla.
Jennifer K CarrollAmerican Academy of Family Physicians National Research Network, Leawood, Kan; Department of Family Medicine, University of Colorado School of Medicine, Aurora, Colo.
Thomas CasaleDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.
Juan C CeledónDivision of Pediatric Pulmonary Medicine, University of Pittsburgh, Pittsburgh, Pa.
Rubin CohenDivision of Pulmonary Critical Care and Sleep Medicine, Syracuse VA Medical Center, SUNY Upstate Medical University, Syracuse, NY.
Tamera Coyne-BeasleyDepartment of Adolescent Medicine, University of North Carolina, Chapel Hill, NC.
Jing CuiDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Mass.
Brianna EricsonDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass.
Paulina HernandezDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass.
David C KaelberCenter for Clinical Informatics Research and Education, MetroHealth System, Cleveland, Ohio; Departments of Medicine, Pediatrics, and Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio.
Nancy MaherDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Mass.
Conner MerrimanDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla.
Giselle MosnaimDivision of Allergy, Asthma, and Immunology, Northshore University Health System, Evanston, Ill.
Sylvette NazarioAllergy and Immunology Section, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Wanda PhipatanakulDepartments of Allergy and Immunology and Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Victor Pinto-PlataDivision of Pulmonary and Critical Care, Lahey Hospital and Medical Center, Burlington, Mass.
Isaretta RileyDivision of Pulmonary and Critical Care Medicine, Duke University School of Medicine, Durham, NC.
Kartik ShenoyTemple Lung Center, Lewis Katz School of Medicine at Temple University, Philadelphia, Pa.
Juan WisniveskyDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Barbara YawnDepartment of Family and Community Health, University of Minnesota, Minneapolis, Minn.
Elliot IsraelDivisions of Pulmonary and Critical Care Medicine and Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Juan Carlos CardetDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla. Electronic address: jcardet@usf.edu.
Brigham and Women's Hospital · USUniversity of South Florida · USBoston Children's Hospital · USNorthShore University HealthSystem · USAmerican Academy of Family Physicians · USDuke University · USIcahn School of Medicine at Mount Sinai · USLahey Hospital and Medical Center · USMetroHealth · USMiami VA Healthcare System · USSUNY Upstate Medical University · USTemple Lung Center · USUniversity of Minnesota · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USUniversity of Pittsburgh · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Enterolactone and AsthmaK23AI125785 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CARDET, JUAN CARLOS · 2017 to 2021
$970k
Coping with Asthma through Life Management (CALM)K01HL159043 · NHLBI · DUKE UNIVERSITY · PI RILEY, ISARETTA · 2021 to 2025
$808k
Social Determinants of Health, Asthma-Related Morbidity and Therapeutic Optimization for Black and Latinx Adults with AsthmaR21HL172124 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI CARDET, JUAN CARLOS · 2024 to 2025
$262k
NCATS NIH HHS UM1 TR004528NHLBI NIH HHS K01 HL159043NHLBI NIH HHS R21 HL172124NIAID NIH HHS K23 AI125785NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

backgroundBlack adults are disproportionately affected by asthma and are often considered a homogeneous group in research studies despite cultural and ancestral differences.

objectiveWe sought to determine if asthma morbidity differs across adults in Black ethnic subgroups.

methodsAdults with moderate-severe asthma were recruited across the continental United States and Puerto Rico for the PREPARE (PeRson EmPowered Asthma RElief) trial. Using self-identifications, we categorized multiethnic Black (ME/B) participants (n = 226) as Black Latinx participants (n = 146) or Caribbean, continental African, or other Black participants (n = 80). African American (AA/B) participants (n = 518) were categorized as Black participants who identified their ethnicity as being American. Baseline characteristics and retrospective asthma morbidity measures (self-reported exacerbations requiring systemic corticosteroids [SCs], emergency department/urgent care [ED/UC] visits, hospitalizations) were compared across subgroups using multivariable regression.

resultsCompared with AA/B participants, ME/B participants were more likely to be younger, residing in the US Northeast, and Spanish speaking and to have lower body mass index, health literacy, and <1 comorbidity, but higher blood eosinophil counts. In a multivariable analysis, ME/B participants were significantly more likely to have ED/UC visits (incidence rate ratio [IRR] = 1.34, 95% CI = 1.04-1.72) and SC use (IRR = 1.27, 95% CI = 1.00-1.62) for asthma than AA/B participants. Of the ME/B subgroups, Puerto Rican Black Latinx participants (n = 120) were significantly more likely to have ED/UC visits (IRR = 1.64, 95% CI = 1.22-2.21) and SC use for asthma (IRR = 1.43, 95% CI = 1.06-1.92) than AA/B participants. There were no significant differences in hospitalizations for asthma among subgroups.

conclusionsME/B adults, specifically Puerto Rican Black Latinx adults, have higher risk of ED/UC visits and SC use for asthma than other Black subgroups.

Indexed as

AsthmaBlack PeopleAdultAfricaBlack or African AmericanCaribbean PeopleEmergency Service, HospitalEthnicityHispanic or LatinoHumansMorbidityPuerto RicoRetrospective StudiesUnited StatesAfrican Americanasthma exacerbationsCaribbean BlackContinental AfricanED visitshealth care disparitieshealth care utilizationhospitalizationsLatinxminority healthsevere persistent asthma

Identifiers

PMID38000696
PMCPMC10922293
OpenAlexW4388934784

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.