Evidence map›Paper›PMID 38000661›Full record

ArticleThe American journal of clinical nutrition2024

Associations of infant feeding practices with abdominal and hepatic fat measures in childhood in the longitudinal Healthy Start Study.

Catherine C Cohen, Kylie K Harrall, Houchun Hu, Deborah H Glueck, Wei Perng, Kartik Shankar, Dana Dabelea

Open access · greenAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  2. Article
  3. Review
  4. Prospective associations of infant food exposures and appetitive traits with early childhood diet quality.The international journal of behavioral nutrition and physical activity · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Catherine C CohenLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: Catherine.Cohen@cuanschutz.edu.
Kylie K HarrallLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Houchun HuDepartment of Radiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Deborah H GlueckLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Wei PerngLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Kartik ShankarDepartment of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Dana DabeleaLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
University of Colorado Anschutz Medical Campus · USColorado School of Public Health · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BRYAN C BERGMAN · 1995 to 2026
$32.6M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
The Early Life Exposome and Childhood Health - The Colorado Healthy Start 3 Cohort StudyUH3OD023248 · OD · UNIVERSITY OF COLORADO DENVER · PI Traci Allison Bekelman, Dana Dabelea · 2018 to 2026
$14.8M
Exploring the Fuel-Mediated Programming of Neonatal GrowthR01DK076648 · NIDDK · UNIVERSITY OF COLORADO DENVER/HSC DENVER · PI DABELEA, DANA · 2009 to 2018
$7.0M
The Early Life Exposome and Childhood Health - The Colorado Healthy Start 3 Cohort StudyUG3OD023248 · OD · UNIVERSITY OF COLORADO DENVER · PI BEKELMAN, TRACI ALLISON, DABELEA, DANA · 2016 to 2024
$5.9M
Metabolic Health during Puberty: the Healthy Start StudyR01DK133235 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Dana Dabelea, MEGAN MORIARTY KELSEY · 2022 to 2026
$3.5M
Lifecourse dietary exposures and offspring hepatic fat in early childhood: a nutrigenomic approachF32DK131757 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COHEN, CATHERINE CIOFFI · 2022 to 2023
$104k
NIDDK NIH HHS F32 DK131757NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK076648NIDDK NIH HHS R01 DK133235NIH HHS UG3 OD023248NIH HHS UH3 OD023248
6 · The paper itself

Abstract

backgroundInfant feeding patterns have been linked with obesity risk in childhood, but associations with precise measures of body fat distribution are unclear.

objectiveWe examined associations of infant feeding practices with abdominal fat and hepatic fat trajectories in childhood.

methodsThis study included 356 children in the Healthy Start Study, a prospective prebirth cohort in Colorado. Infant feeding practices were assessed by postnatal interviews and categorized as any human milk <6 mo compared with ≥6 mo; complementary foods introduced ≤4 mo compared with >4 mo; soda introduced ≤18 mo compared with >18 mo. Abdominal subcutaneous (SAT) and visceral adipose tissue (VAT) areas and hepatic fat (%) were assessed by magnetic resonance imaging in early and middle childhood (median 5 and 9 y old, respectively). We examined associations of infant feeding with adiposity trajectories across childhood using linear mixed models.

resultsIn the sample of children, 67% consumed human milk ≥6 mo, 75% were introduced to complementary foods at >4 mo, and 81% were introduced to soda at >18 mo. We did not find any associations between duration of any human milk consumption and childhood adiposity trajectories. Early introduction to complementary foods (≤4 mo) was associated with faster rates of change for SAT and VAT during childhood (Slope [95% CI]: 15.1 [10.7,19.4] cm

conclusionsThe timing of introduction and quality of complementary foods in infancy was associated with rates of abdominal and hepatic fat accrual during childhood. Experimental studies are needed to assess underlying mechanisms.

Indexed as

AdiposityPediatric ObesityAbdominal FatChildFeeding BehaviorHumansInfantIntra-Abdominal FatLongitudinal StudiesProspective Studiesbody compositionbody fat distributiondevelopmental origins of health and diseasediet qualityectopic fatepidemiologyinfant nutritionmaternal and child healthPediatric

Identifiers

PMID38000661
PMCPMC10884608
OpenAlexW4388943689

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.