ArticleJournal of critical care2024
Recurrent delirium episodes within the intensive care unit: Incidence and associated factors.
Article in Journal of critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Development and validation of a nomogram for predicting subsyndromal delirium in critically ill patients in the emergency department.Internal and emergency medicine · 2026Article
- Article
- A novel nomogram for predicting subsyndromal delirium in critically ill patients with diabetes.Frontiers in endocrinology · 2026Article
- Intranasal Dexmedetomidine as a rescue strategy for established postoperative delirium following loss of intravenous access: a case report.Frontiers in medicine · 2026Article
- A machine learning-based prediction model for sepsis-associated delirium in intensive care unit patients with sepsis-associated acute kidney injury.Renal failure · 2025Observational
- A qualitative study of geriatric specialist nurses' experiences to navigate delirium in the elderly.BMC nursing · 2024Article
- Delirium and Its Associations with Critical Care Utilizations and Outcomes at the Time of Hospital Discharge in Patients with Acute Brain Injury.Medicina (Kaunas, Lithuania) · 2024Article
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Authors and funding
8 authors.
Funding
Abstract
purposeDescribe the incidence and factors associated with recurrent delirium in the intensive care unit (ICU). MATERIALS AND
methodsRetrospective study of ICU patients diagnosed with delirium. Delirium clearance defined as 48 h of negative delirium assessments following initial episode and recurrent delirium as any positive delirium assessment following clearance. Multivariable logistic regression model assessed independent association of patient and hospital factors on development of recurrent delirium, adjusting for pre-defined covariates.
resultsAmong 8591 ICU admissions identified with delirium, 1067 (12.4%) had recurrent symptoms. Factors associated with increased odds of recurrent delirium were age (nonlinear; p = 0.02), shock (OR 1.45, 95% CI [1.20, 1.75]), admission to medical (OR 3.25, 95% CI [2.42, 4.37]), surgical (OR 3.00, 95% CI [2.21, 4.06]), or trauma (OR 2.17, 95% CI [1.58, 3.00]) ICU vs. cardiovascular ICU, increased duration of mechanical ventilation (OR 2.43, 95% CI [2.22, 2.65]), propofol use (OR 1.35, 95% CI [1.02, 1.80]), and antipsychotic medications (haloperidol OR 1.53, 95% CI [1.26, 1.86]; quetiapine OR 2.45, 95% CI [1.98, 3.02]; and olanzapine OR 1.54, 95% CI [1.25, 1.88]).
conclusionsOver 10% of delirious ICU patients had recurrent symptoms. Factors associated with recurrence included age, duration of mechanical ventilation and medication exposure. CLINICAL TRIAL NUMBER: Not applicable.
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