Evidence map›Paper›PMID 37999680›Full record

ArticleJournal of proteome research2024

Comparative Hippocampal Proteome and Phosphoproteome in a Niemann-Pick, Type C1 Mouse Model Reveal Insights into Disease Mechanisms.

Thu T A Nguyen, Varshasnata Mohanty, Ying Yan, Kevin R Francis, Stephanie M Cologna

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thu T A NguyenDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States.
Varshasnata MohantyDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States.ORCID 0000-0002-1520-7974
Ying YanDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States.ORCID 0000-0003-1459-2038
Kevin R FrancisCellular Therapies and Stem Cell Biology Group, Sanford Research, Sioux Falls, South Dakota 57104, United States.ORCID 0000-0002-3636-7264
Stephanie M ColognaDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States.ORCID 0000-0002-3541-3361
University of Illinois Chicago · USUniversity of South Dakota · US

Funding

Yeast 2 HybridP20GM103620 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2013 to 2023
$24.2M
Novel Therapeutic Approaches for NPC DiseaseR01NS124784 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Vinay Aakalu, Stephanie M Cologna · 2022 to 2026
$2.9M
Development of autophagy modulators for evaluation as a therapeutic strategy for Niemann-Pick Type CR01NS114413 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI COLOGNA, STEPHANIE M · 2020 to 2024
$2.0M
NIGMS NIH HHS P20 GM103620NINDS NIH HHS R01 NS114413NINDS NIH HHS R01 NS124784
6 · The paper itself

Abstract

Niemann-Pick disease, type C (NPC) is a neurodegenerative, lysosomal storage disorder in individuals carrying two mutated copies of either the

Indexed as

Niemann-Pick Disease, Type CProteomeAnimalsDisease Models, AnimalHippocampusIntracellular Signaling Peptides and ProteinsMiceIntracellular Signaling Peptides and ProteinsProteomecholesterolNiemann–Pick diseasephosphorylationsynaptic plasticityTMT10plex

Identifiers

PMID37999680
PMCPMC12103818
OpenAlexW4388969273

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.