Evidence map›Paper›PMID 37999617›Full record

ArticleTropical medicine and infectious disease2023

Successful Implementation Strategies in iCARE Nigeria-A Pilot Intervention with Text Message Reminders and Peer Navigation for Youth Living with HIV.

Aima A Ahonkhai, Kehinde M Kuti, Lisa R Hirschhorn, Lisa M Kuhns, Robert Garofalo, Amy K Johnson, Adedotun Adetunji, Baiba Berzins, Ogochukwu Okonkwor, Olutosin Awolude and 2 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  6. Article
  7. User-centered adaption ofAIDS care · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Aima A AhonkhaiDepartment of Medicine, Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN 37203, USA.ORCID 0000-0003-0666-4767
Kehinde M KutiDepartment of Family Medicine, University College Hospital, Ibadan 200005, Nigeria.
Lisa R HirschhornDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-4355-7437
Lisa M KuhnsDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0001-8294-7801
Robert GarofaloDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0001-9513-9416
Amy K JohnsonDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-4247-455X
Adedotun AdetunjiDepartment of Family Medicine, University College Hospital, Ibadan 200005, Nigeria.ORCID 0000-0003-1589-6228
Baiba BerzinsDivision of Infectious Diseases, Northwestern University, Chicago, IL 60611, USA.
Ogochukwu OkonkworDivision of Infectious Diseases, Northwestern University, Chicago, IL 60611, USA.
Olutosin AwoludeDepartment of Obstetrics and Gynecology, College of Medicine, University of Ibadan, Ibadan 200212, Nigeria.
Olayinka OmigbodunDepartment of Psychiatry, College of Medicine, University of Ibadan, Ibadan 200212, Nigeria.
Babafemi O TaiwoDivision of Infectious Diseases, Northwestern University, Chicago, IL 60611, USA.
Northwestern University · USUniversity College Hospital, Ibadan · NGUniversity of Ibadan · NGMassachusetts General Hospital · US

Funding

Intensive Combination Approach to Rollback the Epidemic (iCARE) in Nigerian AdolescentsUH3HD096920 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAIWO, BABAFEMI O · 2020 to 2022
$4.6M
Intensive Combination Approach to Rollback the Epidemic (iCARE) in Nigerian AdolescentsUG3HD096920 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GAROFALO, ROBERT, TAIWO, BABAFEMI O · 2018 to 2020
$2.0M
NICHD NIH HHS UG3 HD096920NICHD NIH HHS UH3 HD096920
6 · The paper itself

Abstract

To address poor outcomes among adolescents and young adults living with HIV (AYA-HIV), iCARE Nigeria successfully piloted two-way text message antiretroviral therapy (ART) reminders together with peer navigation. Study participants had significant improvement in ART adherence and viral suppression at 48 weeks. Understanding facto of this intervention. We used explanatory, mixed methods to assess implementation outcomes (feasibility, acceptability, and adoption) and identify implementation strategies used or adapted to promote intervention success. Quantitative data included participant surveys, program records, and back-end mHealth data, and were summarized using descriptive statistics. Qualitative data were collected from key informants and focus group discussions with program staff and summarized using directed content analysis. iCARE Nigeria was feasible as evidenced by ease of recruitment, high retention of patients and peer navigators (PN), and successful deployment of initial text message reminders (99.9%). Most participants (95%) and PN (90%) found text message reminders were not bothersome or intrusive. Implementation strategies employed to facilitate intervention success included: (1) selecting, training, supervising, and matching of PN to patients; (2) tailoring frequency (daily to weekly) and mode of communication between PN and patients according to patient need; (3) routine screening for adherence challenges; (4) changing phone airtime stipends from monthly to weekly in response to rapid depletion; and (5) conducting telecommunication needs assessments, to identify and troubleshoot implementation barriers (issues with mobile devices, power availability). iCARE Nigeria was feasible and acceptable with high adoption by stakeholders. The implementation strategies identified here can be tailored for intervention scale-up in similar environments to promote ART adherence for AYA-HIV.

Indexed as

adolescents and young adultsHIVimplementation scienceNigeriapeer navigationretention in care

Identifiers

PMID37999617
PMCPMC10675344
OpenAlexW4388731704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.