Evidence map›Paper›PMID 37999615›Full record

ArticleTropical medicine and infectious disease2023

Geographic Mobility and HIV Care Engagement among People Living with HIV in Rural Kenya and Uganda.

James Ayieko, Marguerite Thorp, Monica Getahun, Monica Gandhi, Irene Maeri, Sarah A Gutin, Jaffer Okiring, Moses R Kamya, Elizabeth A Bukusi, Edwin D Charlebois and 4 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

James AyiekoKenya Medical Research Institute, Center for Microbiology Research, Nairobi 00200, Kenya.
Marguerite ThorpDivision of Infectious Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA.
Monica GetahunDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
Monica GandhiDivision of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA.
Irene MaeriKenya Medical Research Institute, Center for Microbiology Research, Nairobi 00200, Kenya.
Sarah A GutinDepartment of Community Health Systems, School of Nursing, University of California, San Francisco, CA 94143, USA.
Jaffer OkiringClinical Epidemiology Unit, School of Medicine, College of Health Sciences, Makerere University, Kampala P.O. Box 7072, Uganda.
Moses R KamyaSchool of Medicine, Makerere University, Kampala P.O. Box 7072, Uganda.
Elizabeth A BukusiKenya Medical Research Institute, Center for Microbiology Research, Nairobi 00200, Kenya.
Edwin D CharleboisCenter for AIDS Prevention Studies, Department of Medicine, University of California, San Francisco, CA 94143, USA.ORCID 0000-0001-7237-2119
Maya PetersenDivision of Biostatistics, University of California, Berkeley, CA 94720, USA.
Diane V HavlirDivision of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA.
Carol S CamlinDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA.
Pamela M MurnaneDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, USA.
University of California, San Francisco · USKenya Medical Research Institute · KEMakerere University · UGUniversity of California, Berkeley · USUniversity of California, Los Angeles · US

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi · 1988 to 2026
$93.6M
Reducing Failure-to-Initiate ART: Streamlined ART Start Strategy (START)U01AI099959 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2012 to 2016
$39.7M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Understanding mobility and risk in SEARCH communitiesR01MH104132 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CAMLIN, CAROL SUZANNE · 2015 to 2019
$3.1M
Implementing a risk score to facilitate enhanced adherence support for pregnant and postpartum women at risk of viremiaK01MH119910 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MURNANE, PAMELA MAE · 2019 to 2023
$922k
Couples Advancing Together for Safer Conception (CAT-SC): A couples’-based intervention to improve engagement in sexual and reproductive health services for mobile fisherfolk in KenyaK01MH132435 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sarah A Gutin · 2023 to 2026
$721k
FIC NIH HHS D43 TW009343NIAID NIH HHS P30 AI027763NIAID NIH HHS U01 AI099959NIAID NIH HHS UM1 AI068636NIH HHS D43TW009343,R01MH104132,K01MH119910,P30AI027763NIMH NIH HHS K01 MH119910NIMH NIH HHS K01 MH132435NIMH NIH HHS R01 MH104132
6 · The paper itself

Abstract

introductionHuman mobility is a critical aspect of existence and survival, but may compromise care engagement among people living with HIV (PLHIV). We examined the association between various forms of human mobility with retention in HIV care and antiretroviral treatment (ART) interruptions.

methodsIn a cohort of adult PLHIV in Kenya and Uganda, we collected surveys in 2016 about past 6-month travel and lifetime migration histories, including reasons and locations, and engagement in HIV care defined as (1) discontinuation of care, and (2) history of a treatment interruption among those who remained in care. We estimated associations between mobility and these care engagement outcomes via logistic regression, adjusted for sex, prior mobility, age, region, marital status, household wealth, and education.

resultsAmong 1081 participants, 56 (5%) reported having discontinued care; among those in care, 104 (10%) reported treatment interruption. Past-year migration was associated with a higher risk of discontinuation of care (adjusted odds ratio [aOR] 1.98, 95% CI 1.08-3.63). In sex-stratified models, the association was somewhat attenuated in women, but remained robust among men. Past-year migration was associated with reduced odds of having a treatment interruption among men (aOR 0.51, 95% CI 0.34-0.77) but not among women (aOR 2.67, 95% CI 0.78, 9.16). Travel in the past 6 months was not associated with discontinuation of care or treatment interruptions.

conclusionsWe observed both negative and protective effects of recent migration on care engagement and ART use that were most pronounced among men in this cohort. Migration can break ties to ongoing care, but for men, who have more agency in the decision to migrate, may foster new care and treatment strategies. Strategies that enable health facilities to support individuals throughout the process of transferring care could alleviate the risk of care disengagement.

Indexed as

HIVhuman mobilityretention in caresex differencestreatment adherence

Identifiers

PMID37999615
PMCPMC10675546
OpenAlexW4388638123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.