Evidence map›Paper›PMID 37999608›Full record

ArticleTropical medicine and infectious disease2023

The Effectiveness of Topical Dimethicone Together with a One Health Approach for the Control of Tungiasis in the Sanumás Communities, Yanomami Territory, Amazon Rainforest: A Real-World Study.

Yago Ranniere Teixeira Santana, Débora Dornelas Belchior Costa Andrade, Daniel Holanda Barroso, Andressa Vieira Silva, Lucas Felipe Carvalho Oliveira, Renata Velôzo Timbó, David Dias Araújo, Rafael Rocha de Andrade, Marcos Antonio Pellegrini, Fabiola Christian Almeida de Carvalho and 2 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yago Ranniere Teixeira SantanaPrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.
Débora Dornelas Belchior Costa AndradePrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0003-3434-2669
Daniel Holanda BarrosoPrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.
Andressa Vieira SilvaPrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.
Lucas Felipe Carvalho OliveiraSecretaria Especial de Saúde Indígena (SESAI), Ministério da Saúde do Brasil, Brasília 70723-040, Brazil.
Renata Velôzo TimbóPrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0003-1989-7412
David Dias AraújoDimensuri Assessoria Técnica, Brasília 70391-900, Brazil.
Rafael Rocha de AndradePrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0001-8594-0015
Marcos Antonio PellegriniPrograma de Pós-Graduação em Ciências da Saúde, Universidade Federal de Roraima, Boa Vista 69304-000, Brazil.
Fabiola Christian Almeida de CarvalhoPrograma de Pós-Graduação em Ciências da Saúde, Universidade Federal de Roraima, Boa Vista 69304-000, Brazil.ORCID 0000-0002-9532-4854
Luciana Pereira Freire MartinsPrograma de Pós-Graduação em Patologia Molecular, Universidade de Brasília, Brasília 70910-900, Brazil.
Ciro Martins GomesPrograma de Pós-Graduação em Ciências Médicas, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0002-3069-6884
Universidade de Brasília · BRUniversidade Federal de Roraima · BRMinistério da Saúde · BR

Funding

National Council for Scientific and Technological Development MS-SCTIE-Decit No. 22/2019, Brazil.
6 · The paper itself

Abstract

backgroundThe success of tungiasis treatment is highly dependent on adequate environmental control.

methodsThis is a real-world observational cohort study designed to monitor the effectiveness of topical dimethicone together with a One Health approach for the control of tungiasis in the Sanumás communities, Amazon rainforest, Brazil. We followed up on 562 indigenous people and 81 domestic dogs for 1.5 years in a 3-month interval. A new molecular method for large-scale soil evaluation was also tested. The control of tungiasis was independently conducted by the Brazilian Ministry of Health and comprised topical dimethicone application (NYDA

resultsA total of 49 of the 562 indigenous people had active tungiasis at enrollment (8.72%). Only three cases of tungiasis resulted in active lesions after the use of topical dimethicone together with the One Health approach, with two cases of recurrence. From the 6-month follow-up and after, soil infestation was not detected.

conclusionsWe conclude that the use of NYDA

Indexed as

Amerindian Peopleneglected diseasesOne Healthtungiasis

Identifiers

PMID37999608
PMCPMC10674387
OpenAlexW4388017311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.