Evidence map›Paper›PMID 37999589›Full record

ArticleToxics2023

Toxic Relationships: Prediction of TBT's Affinity to the Ecdysteroid Receptor of

Nuno Gonçalo de Carvalho Ferreira, Adriano Chessa, Isabel Oliveira Abreu, Luís Oliva Teles, Peter Kille, António Paulo Carvalho, Laura Guimarães

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Ecotoxicological Effects of Potassium Dichromate on the Tadpole ShrimpAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nuno Gonçalo de Carvalho FerreiraInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.
Adriano ChessaInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.
Isabel Oliveira AbreuInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.
Luís Oliva TelesInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-2584-1482
Peter KilleSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK.
António Paulo CarvalhoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-1663-939X
Laura GuimarãesInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-3360-3783
Universidade do Porto · PTCardiff University · GB

Funding

Cardiff University H2020-COFUND-SIRCIW > MINT-512202European Union H2020-COFUND-SIRCIW > MINT-512202Fundação para a Ciência e Tecnologia 2021.02111.CEECINDFundação para a Ciência e Tecnologia SFRH/BD/115529/2016Fundação para a Ciência e Tecnologia UIDB/04423/2020Fundação para a Ciência e Tecnologia UIDP/04423/2020Higher Education Funding Council for Wales Cardiff University Global Challenge Research FundWelsh Government H2020-COFUND-SIRCIW > MINT-512202
6 · The paper itself

Abstract

Tributyltin (TBT) is a biocide introduced in the 1960s in antifouling paints. Despite legislation banning its use, its persistence in the environment still causes significant harm to organisms. Tributyltin is a ligand of retinoid X receptors (RXR) and ecdysteroid receptors (EcRs), which in arthropods act as homologs of RXR. Focusing on Metazoan species, this study used genomic and proteomic information from different sources to compare their three-dimensional structure, phylogenetic distribution, and amino acid sequence alterations. The objective was to identify possible patterns that relate organisms' sensitivity to TBT using the species

Indexed as

comparative genomicscrustaceaphylogenyproteomicstributyltin

Identifiers

PMID37999589
PMCPMC10675633
OpenAlexW4388752840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.