Evidence map›Paper›PMID 37999519›Full record

ArticleToxins2023

Structural Similarities, in Relation with the Cross-Reactivity, of Hymenoptera Allergenic Dipeptidyl Peptidases IV-An Overall Comparison Including a New Dipeptidyl Peptidase IV Sequence from

Rafael I Monsalve, Manuel Lombardero, Lars H Christensen, Beatriz Núñez-Acevedo, David González-de-Olano, Miriam Sobrino-García, Rosita M Castillo-Loja, Susana B Bravo, Manuela Alonso-Sampedro, Carmen Vidal

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. A stinging case of misinterpretation.The journal of allergy and clinical immunology. Global · 2026
    Article
  4. A case series of failures of protective efficacy of venom immunotherapy withThe journal of allergy and clinical immunology. Global · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Rafael I MonsalveResearch and Development, Alk-Abelló A.S., 28037 Madrid, Spain.ORCID 0000-0002-6838-4472
Manuel LombarderoResearch and Development, Alk-Abelló A.S., 28037 Madrid, Spain.ORCID 0000-0001-5386-5321
Lars H ChristensenGlobal Research, ALK-Abelló A/S., 2970 Hørsholm, Denmark.ORCID 0000-0003-4230-7820
Beatriz Núñez-AcevedoAllergology Service, Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, 28702 Madrid, Spain.ORCID 0000-0003-3876-763X
David González-de-OlanoAllergy Service, Hospital Ramón y Cajal, IRYCIS (Instituto Ramón y Cajal de Investigación Sanitaria), 28034 Madrid, Spain.ORCID 0000-0001-6653-4900
Miriam Sobrino-GarcíaAllergology Service, Hospital Universitario de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-8644-8441
Rosita M Castillo-LojaBiosanitary Institute, IBSAL (Instituto de Investigación Biomédica de Salamanca), 37007 Salamanca, Spain.ORCID 0000-0001-6753-5374
Susana B BravoProteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-7615-3079
Manuela Alonso-SampedroResearch Methods Group (RESMET), Health Research Institute of Santiago de Compostela (IDIS), Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS-ISCIII/RD21/0016/0022), University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-0916-4672
Carmen VidalResearch Methods Group (RESMET), Health Research Institute of Santiago de Compostela (IDIS), Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS-ISCIII/RD21/0016/0022), University Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-2844-2754
ALK-Abelló (Spain) · ESInstituto de Investigación Sanitaria de Santiago · ESALK-Abelló (Denmark) · DKComplejo Hospitalario de Salamanca · ESHospital Universitario Infanta Sofía · ESInstituto de Investigación Biomédica de Salamanca · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Dipeptidyl Peptidases IV (DPPIVs), present in many organisms, are minor components in the venoms of Hymenoptera, where they have been identified as cross-reactive allergenic molecules. Considering that the structure of homologous DPPIVs is well characterized, we aimed to explain which regions have higher similarity among these proteins and present a comparison among them, including a new

Indexed as

HymenopteraWaspsAllergensAnimalsBeesDipeptidyl Peptidase 4HumansProteomicsWasp VenomsAllergensDipeptidyl Peptidase 4Wasp Venomsallergencross-reactivityDPPIVHymenopterastructureVespa velutina

Identifiers

PMID37999519
PMCPMC10675595
OpenAlexW4388653894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.