Evidence map›Paper›PMID 37999513›Full record

ArticleToxins2023

Venomous Noodles: The Evolution of Toxins in Nemertea through Positive Selection and Gene Duplication.

Gabriel Gonzalez Sonoda, Eric de Castro Tobaruela, Jon Norenburg, João Paulo Fabi, Sónia C S Andrade

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gabriel Gonzalez SonodaDepartamento de Genética e Biologia Evolutiva, IB-Universidade de São Paulo, São Paulo 05508-090, Brazil.
Eric de Castro TobaruelaFaculdade de Ciências Farmacêuticas, Food Research Center (FoRC), Universidade de São Paulo, São Paulo 05508-080, Brazil.ORCID 0000-0002-0319-4459
Jon NorenburgSmithsonian Institution, Washington, DC 20024, USA.ORCID 0000-0001-7776-1527
João Paulo FabiFaculdade de Ciências Farmacêuticas, Food Research Center (FoRC), Universidade de São Paulo, São Paulo 05508-080, Brazil.ORCID 0000-0002-7430-7756
Sónia C S AndradeDepartamento de Genética e Biologia Evolutiva, IB-Universidade de São Paulo, São Paulo 05508-090, Brazil.ORCID 0000-0002-1302-5261
Universidade de São Paulo · BRSmithsonian Institution · US

Funding

São Paulo Research Foundation 2015/20139-9São Paulo Research Foundation 2018/12502-4São Paulo Research Foundation 2020/06467-1
6 · The paper itself

Abstract

Some, probably most and perhaps all, members of the phylum Nemertea are poisonous, documented so far from marine and benthic specimens. Although the toxicity of these animals has been long known, systematic studies on the characterization of toxins, mechanisms of toxicity, and toxin evolution for this group are scarce. Here, we present the first investigation of the molecular evolution of toxins in Nemertea. Using a proteo-transcriptomic approach, we described toxins in the body and poisonous mucus of the pilidiophoran

Indexed as

Toxins, BiologicalVenomsAnimalsEvolution, MolecularGene DuplicationGene Expression ProfilingPhylogenyTranscriptomeToxins, BiologicalVenomsCytotoxin-AdN/dSgene duplicationmolecular evolutionribbon worms

Identifiers

PMID37999513
PMCPMC10674772
OpenAlexW4388633559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.