Evidence map›Paper›PMID 37999509›Full record

ArticleToxins2023

Assessment of the Adverse Health Effects of Aflatoxin Exposure from Unpackaged Peanut Oil in Guangdong, China.

Zhini He, Zihui Chen, Yunying Mo, Xiaodan Lu, Yanheng Luo, Shaoliang Lin, Yanxu Zhong, Junfeng Deng, Shixiong Zheng, Lei Xia and 6 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Toxics · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Zhini HeFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Zihui ChenInstitute of Public Health, Guangzhou 510060, China.
Yunying MoFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Xiaodan LuFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Yanheng LuoZhaoqing Center for Disease Control and Prevention, Zhaoqing 526060, China.
Shaoliang LinZhaoqing Center for Disease Control and Prevention, Zhaoqing 526060, China.
Yanxu ZhongFood Safety Monitoring and Evaluation Department, Guangxi Zhuang Autonomous Region Centre for Disease Control and Prevention, Nanning 530028, China.
Junfeng DengFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Shixiong ZhengFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Lei XiaSchool of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0003-0394-945X
Hang WuSchool of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0001-6735-3511
Michael N RoutledgeLeicester Medical School, University of Leicester, Leicester LE1 7RH, UK.
Ye HongFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Xiaoyu XianFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Xingfen YangFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Yunyun GongSchool of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0003-4927-5526
Southern Medical University · CNUniversity of Leeds · GBZhaoqing University · CNGuangxi Center for Disease Prevention and Control · CNJiangsu University · CN

Funding

Guangzhou Science and Technology Program Project 202102021049Newton International Fellowship NIF/R5/258
6 · The paper itself

Abstract

Aflatoxins are liver carcinogens and are common contaminants in unpackaged peanut (UPP) oil. However, the health risks associated with consuming aflatoxins in UPP oil remain unclear. In this study, aflatoxin contamination in 143 UPP oil samples from Guangdong Province were assessed via liquid chromatography-tandem mass spectrometry (LC-MS). We also recruited 168 human subjects, who consumed this oil, to measure their liver functions and lipid metabolism status. Aflatoxin B1 (AFB1) was detected in 79.72% of the UPP oil samples, with levels ranging from 0.02 to 174.13 μg/kg. The average daily human intake of AFB1 from UPP oil was 3.14 ng/kg·bw/day; therefore, the incidence of liver cancer, caused by intake of 1 ng/kg·bw/day AFB1, was estimated to be 5.32 cases out of every 100,000 persons per year. Meanwhile, Hepatitis B virus (HBV) infection and AFB1 exposure exerted a synergistic effect to cause liver dysfunction. In addition, the triglycerides (TG) abnormal rate was statistically significant when using AFB1 to estimate daily intake (EDI) quartile spacing grouping (

Indexed as

AflatoxinsAflatoxin B1ChinaFood ContaminationHumansPeanut OilAflatoxin B1AflatoxinsPeanut Oilaflatoxinsliver functionmargin of exposuresynergistic effectunpackaged peanut oil

Identifiers

PMID37999509
PMCPMC10675126
OpenAlexW4388524050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.