Evidence map›Paper›PMID 37999377›Full record

ArticleMarine drugs2023

Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway.

Fatma H Al-Awadhi, Emily F Simon, Na Liu, Ranjala Ratnayake, Valerie J Paul, Hendrik Luesch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. International journal of molecular sciences · 2025
    Article
  4. Oxidative Stress in Brain Function.Antioxidants (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Fatma H Al-AwadhiDepartment of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-8281-4053
Emily F SimonDepartment of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.
Na LiuDepartment of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.
Ranjala RatnayakeDepartment of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-5980-2070
Valerie J PaulSmithsonian Marine Station, Fort Pierce, FL 34949, USA.ORCID 0000-0002-4691-1569
Hendrik LueschDepartment of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-4091-7492
University of Florida · USSmithsonian Marine Station · US

Funding

Novel Targeted Anticancer Agents from Marine CyanobacteriaR01CA172310 · NCI · UNIVERSITY OF FLORIDA · PI HENDRIK LUESCH · 2013 to 2026
$5.8M
NMR console upgrade for structural biology and metabolomicsS10OD028753 · OD · UNIVERSITY OF FLORIDA · PI LONG, JOANNA R · 2020 to 2020
$600k
NCI NIH HHS R01 CA172310NIH HHS R01CA172310NIH HHS S10 OD028753
6 · The paper itself

Abstract

The monounsaturated fatty acid 7(

Indexed as

Fatty AcidsNF-E2-Related Factor 2AnimalsAnti-Inflammatory AgentsHEK293 CellsHumansInflammationKelch-Like ECH-Associated Protein 1LipopolysaccharidesMiceNF-kappa BAnti-Inflammatory AgentsFatty AcidsKeap1 protein, mouseKelch-Like ECH-Associated Protein 1LipopolysaccharidesNF-E2-Related Factor 2NF-kappa Bfatty acidsimmune functioninflammationmarine cyanobacteriamultiple sclerosisNF-κBRNA sequencing

Identifiers

PMID37999377
PMCPMC10672429
OpenAlexW4388200850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.