Evidence map›Paper›PMID 37999140›Full record

SynthesisCurrent oncology (Toronto, Ont.)2023

Clinical and Molecular Features of Morpheaform Basal Cell Carcinoma: A Systematic Review.

Santina Conte, Sarah Ghezelbash, Bonika Nallanathan, Philippe Lefrançois

Abstract readSystematic Review
In one paragraph

Synthesis in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Refractory Morpheaform Basal Cell Carcinoma Successfully Treated with Oral Sonidegib.Clinical, cosmetic and investigational dermatology · 2026
    Article
  4. International journal of molecular sciences · 2025
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Santina ConteFaculty of Medicine and Health Sciences, McGill University, Montreal, QC H3G 2M1, Canada.ORCID 0000-0002-8342-5738
Sarah GhezelbashCancer Axis, Lady Davis Institute for Medical Research, Montreal, QC H3T 1E2, Canada.
Bonika NallanathanCancer Axis, Lady Davis Institute for Medical Research, Montreal, QC H3T 1E2, Canada.
Philippe LefrançoisCancer Axis, Lady Davis Institute for Medical Research, Montreal, QC H3T 1E2, Canada.ORCID 0000-0003-2939-7956

Funding

Cancer Research Society 1057090Fonds de Recherche du Québec - Santé 312768Fonds de Recherche du Québec - Santé 324151Terry Fox Research Institute 3253
6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is the most common skin cancer, with a lifetime risk currently approaching up to 40% in Caucasians. Among these, some clinical and pathological BCC variants pose a higher risk due to their more aggressive biological behavior. Morpheaform BCC (morBCC), also known as sclerosing, fibrosing, or morpheic BCC, represents up to 5-10% of all BCC. Overall, morBCC carries a poorer prognosis due to late presentation, local tissue destruction, tumor recurrence, and higher frequency of metastasis. In this systematic review, we review the epidemiological, clinical, morphological, dermatoscopical, and molecular features of morBCC. After the title and abstract screening of 222 studies and the full-text review of 84 studies, a total of 54 studies met the inclusion criteria and were thus included in this review.

Indexed as

Basal Cell CarcinomaSkin NeoplasmsHumansNeoplasm Recurrence, LocalTranscription FactorsTranscription FactorsBCCfibrosing basal cell carcinomamorpheaform basal cell carcinomamorphoeic basal cell carcinomasclerosing basal cell carcinomaskin cancer

Identifiers

PMID37999140
PMCPMC10670319

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.