Evidence map›Paper›PMID 37999123›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Seven-Year Single-Center Experience of the Efficacy and Safety of Ferric Carboxymaltose in Cancer Patients with Iron-Deficiency Anemia.

Burak Yasin Aktaş, Emine Büşra Ata, Engin Çeşmeci, İbrahim Yahya Çakır, Muharrem Coşkunpınar, Yağmur Tahillioğlu, Gürkan Güner, Deniz Can Güven, Zafer Arık, Neyran Kertmen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Burak Yasin AktaşDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Emine Büşra AtaDepartment of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
Engin ÇeşmeciDepartment of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
İbrahim Yahya ÇakırDepartment of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
Muharrem CoşkunpınarDepartment of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
Yağmur TahillioğluDepartment of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
Gürkan GünerDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Deniz Can GüvenDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Zafer ArıkDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Neyran KertmenDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Ömer DizdarDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.ORCID 0000-0003-0911-9078
Şuayib YalçınDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Sercan AksoyDepartment of Medical Oncology, Hacettepe Cancer Institute, Ankara 06230, Turkey.
Hacettepe University Hospital · TRHacettepe University · TRGuy's and St Thomas' NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia remains an essential concern affecting the quality of life and the survival of cancer patients. Although there are different approaches to treating anemia in cancer patients, the number of studies reporting the efficacy of iron replacement in cancer patients is limited. In this study, the efficacy and safety of iron carboxymaltose, a parenteral iron treatment option, in the treatment of anemia, were examined retrospectively. A total of 1102 adult patients who received IV ferric carboxymaltose treatment at Hacettepe Oncology Hospital between 2014 and 2020 were included. The mean hemoglobin change observed at the end of the 12th week was 1.8 g/dL, and the rate of patients with an increase in hemoglobin of 1 g/dL or more was 72.1%. It was observed that the treatment demonstrated effectiveness in patients receiving active cancer treatment in all tumor types. The treatment was generally safe, and no grade 3-5 side effects were observed in the patients included in the study. According to one of the most extensive series published in the literature, iron carboxymaltose is an efficient and safe alternative for cancer patients with iron-deficiency anemia.

Indexed as

AnemiaAnemia, Iron-DeficiencyNeoplasmsAdultFerric CompoundsHemoglobinsHumansIronMaltoseQuality of LifeRetrospective Studiesferric carboxymaltoseFerric CompoundsHemoglobinsIronMaltosecancer-related anemiaferric carboxymaltoseiron deficiency

Identifiers

PMID37999123
PMCPMC10670613
OpenAlexW4388226415

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.