Evidence map›Paper›PMID 37999100›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Breaking Down Barriers to Detection and Care in Early-Age-Onset Colorectal Cancer in Canada.

Michael J Raphael, Petra Wildgoose, Filomena Servidio-Italiano, Mary A De Vera, Darren Brenner, Monika Slovinec D'Angelo, Robin McGee, Scott Berry, Clarence Wong, Sharlene Gill

Abstract readConference Proceedings
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael J RaphaelSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Petra WildgooseSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Filomena Servidio-ItalianoColorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.
Mary A De VeraFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0002-2205-2683
Darren BrennerDepartment of Community Health Sciences, University of Calgary, Calgary, AB T2N 4N1, Canada.
Monika Slovinec D'AngeloColorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.ORCID 0009-0009-6878-7704
Robin McGeeIndependent Researcher, Port Williams, NS, Canada.
Scott BerryDepartment of Oncology, Carlo Fidani Peel Regional Cancer Centre, Mississauga, ON L5M 7S4, Canada.
Clarence WongDivision of Gastroenterology, University of Alberta, Edmonton, AB T6G 2X8, Canada.ORCID 0000-0003-3191-3294
Sharlene GillDivision of Medical Oncology, BC Cancer, University of British Columbia, Vancouver, BC V5Z 4E6, Canada.ORCID 0000-0003-3306-3617

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The second Early-Age-Onset Colorectal Cancer Symposium, convened in October 2022, sought solutions to the barriers to early detection and care for colorectal cancer in Canada. This meeting built on a previous symposium, held in 2021 and reported in this journal. Early-age-onset colorectal cancer (EAOCRC) affects increasing numbers of people under the age of 50 in Canada and throughout the developed world. Two main themes emerged from the meeting: the importance of timely detection, and the need for a tailored approach to the care of EAOCRC. Early detection is crucial, especially in light of the later stage at diagnosis and unique tumour characteristics. Symposium participants were strongly in favour of reducing the age of eligibility for screening from 50 to 45, and promoting the development of non-invasive screening techniques such as testing for circulating tumour DNA and biomarkers. Leading approaches to care were described and discussed, which meet the unique treatment needs of younger CRC patients. Multidisciplinary practices within and outside Canada address such factors as fertility, family roles, education, careers and financial responsibilities. These models can be applied in treatment centres across the country.

Indexed as

Colorectal NeoplasmsBiomarkersCanadaHumansBiomarkerscolorectal cancerEAO-CRCEAOCRCearly-age-onset colorectal cancerEO-CRC

Identifiers

PMID37999100
PMCPMC10670200

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.