Evidence map›Paper›PMID 37999063›Full record

ArticleInsects2023

Trade-Offs among Immune Mechanisms: Bacterial-Challenged

Lei Zhang, Cynthia L Goodman, Joseph A Ringbauer, Xingfu Jiang, Weixiang Lv, Dianjie Xie, Tamra Reall, David Stanley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insects, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Lei ZhangState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Cynthia L GoodmanBiological Control of Insects Research Laboratory, USDA, Agricultural Research Service, Columbia, MO 65203, USA.
Joseph A RingbauerBiological Control of Insects Research Laboratory, USDA, Agricultural Research Service, Columbia, MO 65203, USA.
Xingfu JiangState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Weixiang LvState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Dianjie XieState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Tamra ReallMU Extension, University of Missouri, Kansas City, MO 64014, USA.
David StanleyBiological Control of Insects Research Laboratory, USDA, Agricultural Research Service, Columbia, MO 65203, USA.
Chinese Academy of Agricultural Sciences · CNBiological Control of Insects Research Laboratory · USAgricultural Research Service · USInstitute of Plant Protection · CNUniversity of Missouri–Kansas City · US

Funding

the National Natural Science Foundation of China 31871951, 32072420the U.S. Department of Agriculture/Agricultural Research Service and by National Key Research and Development Program of China 2021YFD1400701
6 · The paper itself

Abstract

Insect innate immunity is composed of cellular and humoral reactions, the former acting via circulating hemocytes and the latter via immune signaling that lead to the production of antimicrobial peptides and phenol oxidase-driven melanization. Cellular immunity involves direct interactions between circulating hemocytes and invaders; it includes internalization and killing microbes (phagocytosis) and formation of bacterial-laden microaggregates which coalesce into nodules that are melanized and attached to body walls or organs. Nodulation can entail investing millions of hemocytes which must be replaced. We hypothesized that biologically costly hemocyte-based immunity is traded off for behavioral fevers in infected larvae of fall armyworms,

Indexed as

behavioral feverinsect immunitynodulationprostaglandinsSpodoptera frugiperda

Identifiers

PMID37999063
PMCPMC10671956
OpenAlexW4388534405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.