ReviewDentistry journal2023
Prognostic Significance of Histopathological Parameters for Salivary Gland Adenoid Cystic Carcinoma.
Review in Dentistry journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Certainties, Doubts, and Myths in the Diagnosis and Treatment of Salivary Gland Tumors of the Head and Neck.Cancers · 2026Review
- Clinicopathological features and prognostic analysis of 30 patients with laryngeal and hypopharyngeal adenoid cystic carcinoma: a single-center retrospective study.Journal of cancer research and clinical oncology · 2026Article
- Article
- Histological-pathological and clinical T stage of primary adenoid cystic carcinoma of the lacrimal gland in a Chinese population.BMC cancer · 2025Article
- High-Grade Solid Adenoid Cystic Carcinoma of the Larynx: A Case Report.Reports (MDPI) · 2025Article
- Current landscape and future directions of therapeutic approaches for adenoid cystic carcinoma of the salivary glands (Review).Oncology letters · 2025Review
- Primary adenoid cystic carcinoma of the rib with metastases: A rare case report and literature review.Oncology letters · 2025Article
- Long-term survival of subglottic adenoid cystic carcinoma: a case report.Frontiers in oncology · 2025Article
- Ascending Perineural Spread of a Parotid Gland Adenoid Cystic Carcinoma Masquerading as a Local Recurrence of Skull Base Meningioma: Illustrative Case.NMC case report journal · 2025Article
- Characterization of uniquely tumorigenic cancer stem cells in salivary gland adenoid cystic carcinoma.Frontiers in oral health · 2025Article
- Adenoid cystic carcinoma of the parotid and submandibular glands in children and young adults: A population-based study.Pediatric blood & cancer · 2024Article
- Adenoid Cystic Carcinoma of the Sinonasal Cavity: A Case Report and Literature Review.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor that accounts for approximately 1% of all head and neck cancers. Despite its initial indolent behavior, long-term survival is poor due to locoregional recurrence in approximately 40% and distant metastasis in up to 60% of patients who undergo radical treatment. The histological parameters of ACC and the combination of these parameters in histopathological grading systems provide valuable prognostic information about the clinical course of the disease. Within this context, this review aims to analyze the impact of histopathological parameters, individual or combined in histopathological grading systems of malignancy, on ACC prognosis. Individual histopathological parameters such as solid pattern, presence of tumor necrosis, high-grade transformation, dominance of the epithelial component, presence of perineural and lymphovascular invasion, and positive surgical margins have negative impacts on the survival of patients with ACC. There are currently four histopathological grading systems for ACC; however, few studies have validated these systems and most of them explored small cohorts with short follow-up. Considering that the application of grading systems has been associated with ACC prognosis, a broader validation will allow not only their use for prognostic prediction but also assist in treatment planning.
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