Evidence map›Paper›PMID 37998943›Full record

ArticleGels (Basel, Switzerland)2023

Role of pH and Crosslinking Ions on Cell Viability and Metabolic Activity in Alginate-Gelatin 3D Prints.

Andrea Souza, Matthew Parnell, Brian J Rodriguez, Emmanuel G Reynaud

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrea SouzaSchool of Biomolecular and Biomedical Science, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-4906-3032
Matthew ParnellSchool of Biomolecular and Biomedical Science, University College Dublin, D04 V1W8 Dublin, Ireland.
Brian J RodriguezSchool of Physics, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0001-9419-2717
Emmanuel G ReynaudSchool of Biomolecular and Biomedical Science, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0003-1502-661X
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginate-gelatin hydrogels are extensively used in bioengineering. However, despite different formulations being used to grow different cell types in vitro, their pH and its effect, together with the crosslinking ions of these formulations, are still infrequently assessed. In this work, we study how these elements can affect hydrogel stability and printability and influence cell viability and metabolism on the resulting 3D prints. Our results show that both the buffer pH and crosslinking ion (Ca

Indexed as

3D printingalginate–gelatin hydrogelBaCl2CaCl2fluid phaseNIH/3T3pHU2OS

Identifiers

PMID37998943
PMCPMC10670374
OpenAlexW4388193551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.