Evidence map›Paper›PMID 37998862›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

Targeting Mosquitoes through Generation of an Insecticidal RNAi Yeast Strain Using Cas-CLOVER and Super PiggyBac Engineering in

Corey Brizzee, Keshava Mysore, Teresia M Njoroge, Seth McConnell, Majidah Hamid-Adiamoh, Akilah T M Stewart, J Tyler Kinder, Jack Crawford, Molly Duman-Scheel

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Progresses of transposon research inSynthetic and systems biotechnology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Corey BrizzeeDemeetra Ag Bio, 2277 Thunderstick Dr. Suite 300, Lexington, KY 40505, USA.ORCID 0000-0001-8659-7407
Keshava MysoreDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 Notre Dame Ave., South Bend, IN 46617, USA.ORCID 0000-0003-2794-7029
Teresia M NjorogeDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Seth McConnellDemeetra Ag Bio, 2277 Thunderstick Dr. Suite 300, Lexington, KY 40505, USA.
Majidah Hamid-AdiamohDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Akilah T M StewartDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
J Tyler KinderDemeetra Ag Bio, 2277 Thunderstick Dr. Suite 300, Lexington, KY 40505, USA.ORCID 0000-0001-7207-0639
Jack CrawfordDemeetra Ag Bio, 2277 Thunderstick Dr. Suite 300, Lexington, KY 40505, USA.
Molly Duman-ScheelDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 Notre Dame Ave., South Bend, IN 46617, USA.ORCID 0000-0003-1254-5369
University of Notre Dame · US

Funding

Innovative Vector Control Consortium N/AU.S. Army Medical Research Acquisition Activity PRMRP-Expansion Award No. W81XWH-21-2-0038
6 · The paper itself

Abstract

The global deployment of RNAi yeast insecticides involves transitioning from the use of laboratory yeast strains to more robust strains that are suitable for scaled fermentation. In this investigation, the RNA-guided Cas-CLOVER system was used in combination with Piggybac transposase to produce robust

Indexed as

AedesAnophelesCulexengineeringmosquitoesSaccharomyces cerevisiaeshRNAsynthetic biology

Identifiers

PMID37998862
PMCPMC10672312
OpenAlexW4387976258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.