Evidence map›Paper›PMID 37998619›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Recent Advances in the Field of Artificial Intelligence for Precision Medicine in Patients with a Diagnosis of Metastatic Cutaneous Melanoma.

Hayley Higgins, Abanoub Nakhla, Andrew Lotfalla, David Khalil, Parth Doshi, Vandan Thakkar, Dorsa Shirini, Maria Bebawy, Samy Ammari, Egesta Lopci and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Artificial Intelligence Algorithm Predicts Response to Immune Checkpoint Inhibitors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Hayley HigginsDepartment of Clinical Medicine, Touro College of Osteopathic Medicine, Middletown, NY 10940, USA.
Abanoub NakhlaDepartment of Clinical Medicine, American University of the Caribbean School of Medicine, 33027 Cupecoy, Sint Maarten, The Netherlands.
Andrew LotfallaDepartment of Clinical Medicine, Touro College of Osteopathic Medicine, Middletown, NY 10940, USA.
David KhalilDepartment of Clinical Medicine, Campbell University School of Osteopathic Medicine, Lillington, NC 27546, USA.
Parth DoshiDepartment of Clinical Medicine, Campbell University School of Osteopathic Medicine, Lillington, NC 27546, USA.
Vandan ThakkarDepartment of Clinical Medicine, Campbell University School of Osteopathic Medicine, Lillington, NC 27546, USA.
Dorsa ShiriniDepartment of Radiology, Shahid Beheshti University of Medical Sciences, Tehran 1981619573, Iran.
Maria BebawyDepartment of Clinical Medicine, Touro College of Osteopathic Medicine, Middletown, NY 10940, USA.
Samy AmmariDépartement d'Imagerie Médicale Biomaps, UMR1281 INSERM, CEA, CNRS, Gustave Roussy, Université Paris-Saclay, 94800 Villejuif, France.ORCID 0000-0002-1506-0714
Egesta LopciNuclear Medicine Unit, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0001-9732-1094
Lawrence H SchwartzDepartment of Radiology, New York-Presbyterian, Columbia University Irving Medical Center, New York, NY 10032, USA.
Michael PostowMelanoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Laurent DercleDepartment of Radiology, Shahid Beheshti University of Medical Sciences, Tehran 1981619573, Iran.ORCID 0000-0002-1322-0710
Campbell University · USTouro College · USShahid Beheshti University of Medical Sciences · IRAmerican University of the Caribbean School of Medicine · SXCentre National de la Recherche Scientifique · FRColumbia University Irving Medical Center · USIRCCS Humanitas Research Hospital · ITMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Standard-of-care medical imaging techniques such as CT, MRI, and PET play a critical role in managing patients diagnosed with metastatic cutaneous melanoma. Advancements in artificial intelligence (AI) techniques, such as radiomics, machine learning, and deep learning, could revolutionize the use of medical imaging by enhancing individualized image-guided precision medicine approaches. In the present article, we will decipher how AI/radiomics could mine information from medical images, such as tumor volume, heterogeneity, and shape, to provide insights into cancer biology that can be leveraged by clinicians to improve patient care both in the clinic and in clinical trials. More specifically, we will detail the potential role of AI in enhancing detection/diagnosis, staging, treatment planning, treatment delivery, response assessment, treatment toxicity assessment, and monitoring of patients diagnosed with metastatic cutaneous melanoma. Finally, we will explore how these proof-of-concept results can be translated from bench to bedside by describing how the implementation of AI techniques can be standardized for routine adoption in clinical settings worldwide to predict outcomes with great accuracy, reproducibility, and generalizability in patients diagnosed with metastatic cutaneous melanoma.

Indexed as

artificial intelligenceimmunotherapymetastatic melanomaradiology

Identifiers

PMID37998619
PMCPMC10670510
OpenAlexW4388824944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.