Evidence map›Paper›PMID 37998552›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Diagnostic Accuracy of Up-Front PET/CT and MRI for Detecting Cervical Lymph Node Metastases in T1-T2 Oral Cavity Cancer-A Prospective Cohort Study.

Christoffer Bing Madsen, Max Rohde, Oke Gerke, Christian Godballe, Jens Ahm Sørensen

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Diagnostic imaging modalities to detect regional nodal involvement in oral squamous cell carcinoma: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Alterations inCancers · 2025
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christoffer Bing MadsenDepartment of Plastic Surgery, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0003-1088-9512
Max RohdeDepartment of ORL-Head & Neck Surgery and Audiology, Odense University Hospital, 5000 Odense, Denmark.
Oke GerkeDepartment of Nuclear Medicine, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0001-6335-3303
Christian GodballeDepartment of ORL-Head & Neck Surgery and Audiology, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0001-7639-6337
Jens Ahm SørensenDepartment of Plastic Surgery, Odense University Hospital, 5000 Odense, Denmark.ORCID 0000-0003-4903-0094
University of Southern Denmark · DK

Funding

Danish Cancer Society R267-A15386
6 · The paper itself

Abstract

The diagnostic accuracy of up-front 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) for detecting cervical lymph node metastases in patients with T1-T2 oral squamous cell carcinoma is reported with large discrepancies across the literature. We investigated the sensitivity, specificity, positive and negative predictive value, and accuracy of up-front PET/CT for detecting cervical lymph node metastases in this patient group and compared the performance to magnetic resonance imaging (MRI). In this prospective cohort study, 76 patients with T1-T2 oral squamous cell carcinoma underwent an up-front PET/CT and MRI at the Odense University Hospital from September 2013 to February 2016. Sentinel node biopsy and elective neck dissection were used for histopathological verification of the imaging modalities. Up-front PET/CT was significantly more sensitive than neck MRI (74% vs. 27%,

Indexed as

diagnostic accuracyMRIoral canceroral squamous cell carcinomaPET/CTsensitivitysentinel node biopsyspecificity

Identifiers

PMID37998552
PMCPMC10670676
OpenAlexW4388540822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.