Evidence map›Paper›PMID 37998542›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Subserosal Layer and/or Pancreatic Invasion Based on Anatomical Features as a Novel Prognostic Indicator in Patients with Distal Cholangiocarcinoma.

Hisamichi Yoshii, Hideki Izumi, Rika Fujino, Makiko Kurata, Chie Inomoto, Tomoko Sugiyama, Toshio Nakagohri, Eiji Nomura, Masaya Mukai, Takuma Tajiri

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hisamichi YoshiiDepartment of Gastroenterological Surgery, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.ORCID 0000-0002-7849-4982
Hideki IzumiDepartment of Gastroenterological Surgery, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Rika FujinoDepartment of Gastroenterological Surgery, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Makiko KurataDepartment of Diagnostic Pathology, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Chie InomotoDepartment of Diagnostic Pathology, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Tomoko SugiyamaDepartment of Diagnostic Pathology, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Toshio NakagohriDepartment of Gastroenterological Surgery, Tokai University Hospital, Isehara 259-1193, Japan.
Eiji NomuraDepartment of Gastroenterological Surgery, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Masaya MukaiDepartment of Gastroenterological Surgery, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Takuma TajiriDepartment of Diagnostic Pathology, Tokai University Hachioji Hospital, Tokyo 192-0032, Japan.
Tokai University Hachioji Hospital · JPTokai University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The American Joint Committee on Cancer (AJCC) 8th edition T-staging system for distal cholangiocarcinoma (DCC) proposes classification according to the depth of invasion (DOI); nevertheless, DOI measurement is complex and irreproducible. This study focused on the fibromuscular layer and evaluated whether the presence or absence of penetrating fibromuscular invasion of DCC contributes to recurrence and prognosis. In total, 55 patients pathologically diagnosed with DCC who underwent surgical resection from 2002 to 2022 were clinicopathologically examined. Subserosal layer and/or pancreatic (SS/Panc) invasion, defined as penetration of the fibromuscular layer and invasion of the subserosal layer or pancreas by the cancer, was assessed with other clinicopathological prognostic factors to investigate recurrence and prognostic factors. According to the AJCC 8th edition, there were 11 T1, 28 T2, and 16 T3 cases, with 44 (80%) cases of SS/Panc invasion. The DOI was not significantly different for both recurrence and prognostic factors. In the multivariate analysis, only SS/Panc was identified as an independent factor for prognosis (hazard ratio: 16.1; 95% confidence interval: 2.1-118.8,

Indexed as

AJCC 8th editiondepth of invasionfibromuscular layerprognostic markerSS/Panc invasionT-staging system

Identifiers

PMID37998542
PMCPMC10670817
OpenAlexW4388532972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.