Evidence map›Paper›PMID 37998538›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Development and Validation of a Predictive Model Based on LASSO Regression: Predicting the Risk of Early Recurrence of Atrial Fibrillation after Radiofrequency Catheter Ablation.

Mengdie Liu, Qianqian Li, Junbao Zhang, Yanjun Chen

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Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

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9citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mengdie LiuMedicine School, Shenzhen University, Shenzhen 518000, China.
Qianqian LiDepartment of Cardiovascular Medicine, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Junbao ZhangDepartment of Cardiovascular Medicine, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Yanjun ChenDepartment of Cardiovascular Medicine, Peking University Shenzhen Hospital, Shenzhen 518000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough recurrence rates after radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF) remain high, there are a limited number of novel, high-quality mathematical predictive models that can be used to assess early recurrence after RFCA in patients with AF. PURPOSE: To identify the preoperative serum biomarkers and clinical characteristics associated with post-RFCA early recurrence of AF and develop a novel risk model based on least absolute shrinkage and selection operator (LASSO) regression to select important variables for predicting the risk of early recurrence of AF after RFCA.

methodsThis study collected a dataset of 136 atrial fibrillation patients who underwent RFCA for the first time at Peking University Shenzhen Hospital from May 2016 to July 2022. The dataset included clinical characteristics, laboratory results, medication treatments, and other relevant parameters. LASSO regression was performed on 100 cycles of data. Variables present in at least one of the 100 cycles were selected to determine factors associated with the early recurrence of AF. Then, multivariable logistic regression analysis was applied to build a prediction model introducing the predictors selected from the LASSO regression analysis. A nomogram model for early post-RFCA recurrence in AF patients was developed based on visual analysis of the selected variables. Internal validation was conducted using the bootstrap method with 100 resamples. The model's discriminatory ability was determined by calculating the area under the curve (AUC), and calibration analysis and decision curve analysis (DCA) were performed on the model.

resultsIn a 3-month follow-up of AF patients (

conclusionsWe have developed and validated a risk prediction model for the early recurrence of AF after RFCA, demonstrating strong clinical applicability and diagnostic performance. This model plays a crucial role in guiding physicians in preoperative assessment and clinical decision-making. This novel approach also provides physicians with personalized management recommendations.

Indexed as

atrial fibrillationearly recurrenceLASSO regressionnomogramradiofrequency ablation

Identifiers

PMID37998538
PMCPMC10670080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.