ReviewJournal of cardiovascular development and disease2023
The Atrioventricular Conduction Axis Revisited for the 21st Century.
Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- The anatomical variability of the membranous septum in the normal human fetal heart is due to the size and shape of the septal components.Anatomy & cell biology · 2026Article
- Electrocardiographic Characteristics of Escape Rhythm During Complete Atrioventricular Block After Transcatheter Aortic Valve Replacement.Reviews in cardiovascular medicine · 2026Article
- The Anatomy of the Atrioventricular Node.Journal of cardiovascular development and disease · 2025Review
- Electroanatomic Mapping of the Atrioventricular Node and Right Inferior Nodal Extension: Insights from a Case Series.Arrhythmia & electrophysiology review · 2025Article
- The Atrioventricular Conduction Axis in Man and Mouse.Journal of cardiovascular development and disease · 2024Review
- The clinical anatomy of the atrioventricular conduction axis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Revisiting the Atrioventricular Conduction Axis for the 21st Century.Arrhythmia & electrophysiology review · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although first described in the final decade of the 19th century, the axis responsible for atrioventricular conduction has long been the source of multiple controversies. Some of these continue to reverberate. When first described by His, for example, many doubted the existence of the bundle we now name in his honour, while Kent suggested that multiple pathways crossed the atrioventricular junctions in the normal heart. It was Tawara who clarified the situation, although many of his key definitions have not universally been accepted. In key studies in the third decade of the 20th century, Mahaim then suggested the presence of ubiquitous connections that provided "paraspecific" pathways for atrioventricular conduction. In this review, we show the validity of these original investigations, based on our own experience with a large number of datasets from human hearts prepared by serial histological sectioning. Using our own reconstructions, we show how the atrioventricular conduction axis can be placed back within the heart. We emphasise that newly emerging techniques will be key in providing the resolution to map cellular detail to the gross evidence provided by the serial sections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.