Evidence map›Paper›PMID 37998484›Full record

ArticleHealthcare (Basel, Switzerland)2023

Rubella Vaccine Uptake among Women of Childbearing Age in Healthcare Settings.

Cristiana Ferrari, Giuseppina Somma, Sandro Gentili, Gianmarco Manili, Gaetano Mauro, Michele Treglia, Marco Trabucco Aurilio, Andrea Magrini, Luca Coppeta

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Cristiana FerrariDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-2292-3338
Giuseppina SommaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Sandro GentiliDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Gianmarco ManiliDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Gaetano MauroDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Michele TregliaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Marco Trabucco AurilioOffice of Medical Forensic Coordination, Italian National Social Security Institute (INPS), 00144 Rome, Italy.ORCID 0000-0003-2327-1455
Andrea MagriniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Luca CoppetaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-2470-6107
University of Rome Tor Vergata · ITIstituto Nazionale della Previdenza Sociale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRubella is a contagious viral infection that occurs most often in children and young adults. Rubella is the leading vaccine-preventable cause of birth defects. Rubella infection in pregnant women may cause fetal death or congenital defects known as congenital rubella syndrome. There is no specific treatment for rubella, but the disease is preventable by vaccination with an efficacy of over 95%. Vaccination coverage is still below the recommended levels and many cases have occurred worldwide. The COVID-19 pandemic has had a negative impact on the immunization programs and the quality of disease surveillance worldwide. Operators of the healthcare setting are at increased risk of infection due to their work duties and should receive preventive vaccination or serologic protection to work in a healthcare setting.

aimsTo evaluate the serological evidence of rubella IgG antibodies in female healthcare operators of childbearing age, to assess the risk of a breakthrough infection and the need for an additional dose of vaccine.

methodsWe collected age and antibody titers from 449 young female operators aged <50 years who underwent the periodic surveillance at the Occupational Medicine Unit of the Policlinico Tor Vergata, Rome, from January to July 2022. Subjects were considered immune if the anti-rubella IgG titer was >11.00 IU/mL.

resultsThe rate of serologically unprotected subjects was 9.13% (41/449). The mean age of protected subjects was 26.93 years, while the mean age of unprotected subjects was 28.24 years. Age did not correlate with mean titer on statistical analysis (

conclusionsProtection against rubella was suboptimal among female healthcare workers of childbearing age. Acceptance of the rubella vaccine among these operators was low. Most of those who were hesitant intended to postpone the vaccination, while a minority had negative attitudes toward vaccination. A policy of mandatory vaccination policy should overcome the reluctance of operators.

Indexed as

hesitancyimmunity for rubellarubellarubella vaccinevaccination strategyvaccine acceptance

Identifiers

PMID37998484
PMCPMC10671143
OpenAlexW4388831305

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.