Evidence map›Paper›PMID 37998476›Full record

ArticleHealthcare (Basel, Switzerland)2023

Distal Femur Megaprostheses in Orthopedic Oncology: Evaluation of a Standardized Post-Operative Rehabilitation Protocol.

Lorenzo Andreani, Edoardo Ipponi, Federico Falcinelli, Sara Barderi, Lorenzo Vannucci, Francesco Rosario Campo, Antonio D'Arienzo, Paolo Domenico Parchi

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The functional recovery trajectory in patients undergoing lower limb salvage surgery for bone tumour: an observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  4. Article
  5. Review
  6. Article
  7. Revolutionizing bone tumor management: cutting-edge breakthroughs in limb-saving treatments.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lorenzo AndreaniDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-8268-6987
Edoardo IpponiDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-2107-6357
Federico FalcinelliDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0009-0009-0342-2499
Sara BarderiDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.
Lorenzo VannucciDepartment of Rehabilitation and Physical Therapy, University of Pisa, 56126 Pisa, Italy.
Francesco Rosario CampoDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.
Antonio D'ArienzoDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-1016-5944
Paolo Domenico ParchiDepartment of Orthopedics and Trauma Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7560-7104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesMegaprostheses are the most used reconstructive approach for patients who have undergone massive resection of their distal femurs due to bone tumors. Although the literature about their outcomes has flourished in recent decades, to date, a consensus on rehabilitative treatment is yet to be established. In this study, we report on our experience with our latest standardized rehabilitation program, evaluating our results in a mid-to-long-term scenario. MATERIALS AND

methodsWe evaluated the functional results of all our oncologic patients treated between 2016 and 2022 who could follow our standardized post-operative rehabilitative approach, consisting of progressive knee mobilization and early weight-bearing.

resultsSixteen cases were included in our study. The average duration of the patients' hospitalization was 12.2 days. A standing position was reached on average 4.1 days after surgery, while assisted walking was started 4.5 days after surgery. After a mean post-operative follow-up of 46.7 months, our patients' mean MSTS score was 23.2 (10-30). Our data suggest that the sooner patients could achieve a standing position (R = -0.609;

conclusionsRehabilitation should be considered a pivotal factor in decreeing the success of distal femur megaprosthetic implants in long-surviving oncologic patients. Correct rehabilitation, focused on early mobilization and progressive weight-bearing, is crucial to maximizing the post-operative functional outcomes of these patients.

Indexed as

functionalitymegaprosthesisorthopedic oncologyphysical therapyrehabilitation

Identifiers

PMID37998476
PMCPMC10671754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.