Evidence map›Paper›PMID 37998391›Full record

ReviewCells2023

Histopathological Markers for Target Therapies in Primary Cutaneous Lymphomas.

Benedetta Sonego, Adalberto Ibatici, Giulia Rivoli, Emanuele Angelucci, Simona Sola, Cesare Massone

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benedetta SonegoDermatology Clinic, University of Trieste, 35125 Trieste, Italy.ORCID 0000-0001-6892-1445
Adalberto IbaticiUO Ematologia e Terapie Cellulari, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Giulia RivoliUO Ematologia e Terapie Cellulari, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Emanuele AngelucciUO Ematologia e Terapie Cellulari, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-6512-6080
Simona SolaSurgical Pathology, Galliera Hospital, 16128 Genoa, Italy.
Cesare MassoneDermatology Unit & Scientific Directorate, Galliera Hospital, 16128 Genoa, Italy.
Ospedale Policlinico San Martino · ITEnte Ospedaliero Ospedali Galliera · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, targeted (biological) therapies have become available also for primary cutaneous T-cell lymphomas (PCTCLs) including anti-CD30 (brentuximab vedotin) in mycosis fungoides, primary cutaneous anaplastic large T-cell lymphoma, lymphomatoid papulosis; anti-CCR4 (mogamulizumab) in Sezary syndrome; anti-CD123 (tagraxofusp) in blastic plasmocytoid cell neoplasm. Moreover, anti-PD1 (nivolumab), anti-PDL1 (pembrolizumab, atezolizumab), anti-CD52 (alemtuzumab), anti-KIR3DL2-CD158k (lacutamab), and anti-CD70 (cusatuzumab) have been tested or are under investigations in phase II trials. The expression of these epitopes on neoplastic cells in skin biopsies or blood samples plays a central role in the management of PCTCL patients. This narrative review aims to provide readers with an update on the latest advances in the newest therapeutic options for PCTCLs.

Indexed as

Antineoplastic AgentsMycosis FungoidesSezary SyndromeSkin NeoplasmsAntibodies, MonoclonalBrentuximab VedotinHumansAntibodies, MonoclonalAntineoplastic AgentsBrentuximab Vedotinatezolizumabbrentuximab vedotinlacutamablymphomatoid papulosismogamulizumabmycosis fungoidesnivolumabpembrolizumabprimary cutaneous anaplastic large T-cell lymphomatagraxofusp

Identifiers

PMID37998391
PMCPMC10670482
OpenAlexW4388832653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.