Evidence map›Paper›PMID 37998371›Full record

ArticleCells2023

Engineering of

Cedric Woudstra, Anders Nørgaard Sørensen, Lone Brøndsted

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cedric WoudstraDepartment of Veterinary and Animal Sciences, University of Copenhagen, 1870 Frederiksberg C, Denmark.ORCID 0000-0002-3673-6082
Anders Nørgaard SørensenDepartment of Veterinary and Animal Sciences, University of Copenhagen, 1870 Frederiksberg C, Denmark.
Lone BrøndstedDepartment of Veterinary and Animal Sciences, University of Copenhagen, 1870 Frederiksberg C, Denmark.ORCID 0000-0002-7930-5725
University of Copenhagen · DK

Funding

Danmarks Frie Forskningsfond 9041-00159B
6 · The paper itself

Abstract

Due to the extensive use of antibiotics, the increase of infections caused by antibiotic-resistant bacteria is now a global health concern. Phages have proven useful for treating bacterial infections and represent a promising alternative or complement to antibiotic treatment. Yet, other alternatives exist, such as bacteria-produced non-replicative protein complexes that can kill their targeted bacteria by puncturing their membrane (Tailocins). To expand the repertoire of Tailocins available, we suggest a new approach that transforms phages into Tailocins. Here, we genetically engineered the virulent

Indexed as

Anti-Infective AgentsBacteriophagesSalmonella PhagesAnti-Bacterial AgentsBacteriaSalmonellaAnti-Bacterial AgentsAnti-Infective AgentsAckermannviridaebacteriocingenetic engineeringhead-less phageTailocin

Identifiers

PMID37998371
PMCPMC10670071
OpenAlexW4388731992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.