Evidence map›Paper›PMID 37998364›Full record

ArticleCells2023

Impact of Germline Depletion of Bonus on Chromatin State in

Baira Godneeva, Katalin Fejes Tóth, Baiyi Quan, Tsui-Fen Chou, Alexei A Aravin

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harbor perspectives in biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Baira GodneevaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Katalin Fejes TóthDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Baiyi QuanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Tsui-Fen ChouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0003-2410-2186
Alexei A AravinDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-6956-8257
California Institute of Technology · US

Funding

Molecular Mechanism of the piRNA BiogenesisR01GM097363 · NIGMS · CORNELL UNIVERSITY · PI ARAVIN, ALEXEI A. · 2011 to 2025
$4.0M
Understanding the mechanism of Piwi-induced transcriptional silencingR01GM110217 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI FEJES TOTH, KATALIN · 2014 to 2024
$3.1M
NIGMS NIH HHS R01 GM097363NIGMS NIH HHS R01 GM110217NIH HHS R01 GM097363
6 · The paper itself

Abstract

Gene expression is controlled via complex regulatory mechanisms involving transcription factors, chromatin modifications, and chromatin regulatory factors. Histone modifications, such as H3K27me3, H3K9ac, and H3K27ac, play an important role in controlling chromatin accessibility and transcriptional output. In vertebrates, the Transcriptional Intermediary Factor 1 (TIF1) family of proteins play essential roles in transcription, cell differentiation, DNA repair, and mitosis. Our study focused on Bonus, the sole member of the TIF1 family in

Indexed as

ChromatinHistonesAnimalsDrosophilaDrosophila ProteinsFemaleHistone CodeOvaryBon protein, DrosophilaChromatinDrosophila ProteinsHistonesBonuschromatingene expressionH3K27acH3K27me3H3K9actranscription

Identifiers

PMID37998364
PMCPMC10670193
OpenAlexW4388694895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.