Evidence map›Paper›PMID 37998338›Full record

ArticleCells2023

Yuki Azumi, Yu-Ichiro Koma, Shuichi Tsukamoto, Yu Kitamura, Nobuaki Ishihara, Keitaro Yamanaka, Takashi Nakanishi, Shoji Miyako, Satoshi Urakami, Kohei Tanigawa and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yuki AzumiDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Yu-Ichiro KomaDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-3022-8466
Shuichi TsukamotoDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-6192-7542
Yu KitamuraDivision of Gastro-Intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Nobuaki IshiharaDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Keitaro YamanakaDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Takashi NakanishiDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Shoji MiyakoDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-1081-0379
Satoshi UrakamiDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kohei TanigawaDivision of Gastro-Intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Takayuki KodamaDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-6518-5574
Mari NishioDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-7413-0751
Manabu ShigeokaDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Yoshihiro KakejiDivision of Gastro-Intestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0002-2727-0241
Hiroshi YokozakiDivision of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.ORCID 0000-0001-5276-3331
Kobe University · JP

Funding

Japan Society for the Promotion of Science 20K07373Japan Society for the Promotion of Science 22K06978Takeda Science Foundation no number
6 · The paper itself

Abstract

Tumor-associated macrophages (TAMs), one of the major components of the tumor microenvironment, contribute to the progression of esophageal squamous cell carcinoma (ESCC). We previously established a direct co-culture system of human ESCC cells and macrophages and reported the promotion of malignant phenotypes, such as survival, growth, and migration, in ESCC cells. These findings suggested that direct interactions between cancer cells and macrophages contribute to the malignancy of ESCC, but its underlying mechanisms remain unclear. In this study, we compared the expression levels of the interferon-induced genes between mono- and co-cultured ESCC cells using a cDNA microarray and found that interferon-inducible protein 16 (

Indexed as

Carcinoma, Squamous CellEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaCell Line, TumorHumansInterferonsInterleukin-1alphaMacrophagesNeoplastic ProcessesNuclear ProteinsPhosphoproteinsTumor MicroenvironmentIFI16 protein, humanIL1A protein, humanInterferonsInterleukin-1alphaNuclear ProteinsPhosphoproteinsdirect co-cultureesophageal squamous cell carcinomaIFI16IL-1αtumor-associated macrophage

Identifiers

PMID37998338
PMCPMC10670642
OpenAlexW4388635071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.