Evidence map›Paper›PMID 37998000›Full record

ArticleBiology2023

Endothelin Modulates Rhythm Disturbances and Autonomic Responses to Acute Emotional Stress in Rats.

Eleni-Taxiarchia Mouchtouri, Thomas Konstantinou, Panagiotis Lekkas, Alexandra Lianopoulou, Zoi Kotsaridou, Iordanis Mourouzis, Constantinos Pantos, Theofilos M Kolettis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Coumarins in hypertension management: from vascular signaling pathways to clinical perspectives.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eleni-Taxiarchia MouchtouriDepartment of Cardiology, Medical School, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0003-4859-5878
Thomas KonstantinouDepartment of Cardiology, Medical School, University of Ioannina, 45500 Ioannina, Greece.
Panagiotis LekkasCardiovascular Research Institute, 45500 Ioannina, Greece.ORCID 0000-0002-2285-0060
Alexandra LianopoulouSchool of Applied Biology and Biotechnology, Agricultural University of Athens, 10447 Athens, Greece.
Zoi KotsaridouSchool of Applied Biology and Biotechnology, Agricultural University of Athens, 10447 Athens, Greece.
Iordanis MourouzisDepartment of Pharmacology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Constantinos PantosDepartment of Pharmacology, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Theofilos M KolettisDepartment of Cardiology, Medical School, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0002-6680-9131
University of Ioannina · GRAgricultural University of Athens · GRNational and Kapodistrian University of Athens · GR

Funding

Cardiovascular Research Institute, Ioannina, Greece 2021European Union IKY Scholarship Programme
6 · The paper itself

Abstract

The ubiquitous peptide endothelin is currently under investigation as a modulatory factor of autonomic responses to acute emotional stress. Baseline plasma levels of endothelin alter blood pressure responses, but it remains unclear whether autonomic activity and arrhythmogenesis (i.e., brady- or tachyarrhythmias) are affected. We recorded sympathetic and vagal indices (derived from heart rate variability analysis), rhythm disturbances, voluntary motion, and systolic blood pressure after acute emotional stress in conscious rats with implanted telemetry devices. Two strains were compared, namely wild-type and ET

Indexed as

acute emotional stressbradyarrhythmiasendothelinsympathetic activitytachyarrhythmiasvagal activity

Identifiers

PMID37998000
PMCPMC10669295
OpenAlexW4388379728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.