Evidence map›Paper›PMID 37997665›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Vaccine effectiveness against COVID-19 hospitalisation in adults (≥ 20 years) during Omicron-dominant circulation: I-MOVE-COVID-19 and VEBIS SARI VE networks, Europe, 2021 to 2022.

Angela Mc Rose, Nathalie Nicolay, Virginia Sandonis Martín, Clara Mazagatos, Goranka Petrović, Joaquin Baruch, Sarah Denayer, Lucie Seyler, Lisa Domegan, Odile Launay and 52 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

62 authors.

Angela Mc RoseEpiconcept, Paris, France.
Nathalie NicolayEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Virginia Sandonis MartínNational Centre for Microbiology, Institute of Health Carlos III, Madrid, Spain.
Clara MazagatosNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain.
Goranka PetrovićCroatian Institute of Public Health, Zagreb, Croatia.
Joaquin BaruchIDCU within Health promotion and disease prevention Directorate, G'mangia, Malta.
Sarah DenayerSciensano, Brussels, Belgium.
Lucie SeylerUniversitair Ziekenhuis Brussel, Brussels, Belgium.
Lisa DomeganHealth Service Executive-Health Protection Surveillance Centre, Dublin, Ireland.
Odile LaunayInserm, CIC Cochin-Pasteur, Paris, France.
Ausenda MachadoNational Institute of Health Dr Ricardo Jorge, Lisbon, Portugal.
Cristina BurguiInstituto de Salud Pública de Navarra-IdiSNA, Pamplona, Spain.
Roberta VaikutyteLithuanian University of Health Sciences, Kaunas, Lithuania.
F Annabel NiessenCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Isabela I LoghinSt. Parascheva Clinical Hospital of Infectious Diseases, Iasi, Romania.
Petr HusaFaculty of Medicine, Masaryk University, Brno, Czechia.
Nassera AoualiLuxembourg Institute of Health, Luxembourg.
George PanagiotakopoulosNational Public Health Organisation (EODY), Athens, Greece.
Kristin TolksdorfRobert Koch Institute, Berlin, Germany.
Judit Krisztina HorváthNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Jennifer HowardEpiconcept, Paris, France.
Francisco PozoNational Centre for Microbiology, Institute of Health Carlos III, Madrid, Spain.
Virtudes GallardoDirección General de Salud Pública y Ordenación Farmacéutica, Junta de Andalucía, Spain.
Diana NonkovićTeaching Public Health Institute of Split-Dalmatia County, Split, Croatia.
Aušra DžiugytėIDCU within Health promotion and disease prevention Directorate, G'mangia, Malta.
Nathalie BossuytSciensano, Brussels, Belgium.
Thomas DemuyserUniversitair Ziekenhuis Brussel, Brussels, Belgium.
Róisín DuffyHealth Service Executive-Health Protection Surveillance Centre, Dublin, Ireland.
Liem Binh Luong NguyenAP-HP, Hôpital Cochin, Paris, France.
Irina KislayaNational Institute of Health Dr Ricardo Jorge, Lisbon, Portugal.
Iván Martínez-BazInstituto de Salud Pública de Navarra-IdiSNA, Pamplona, Spain.
Giedre GefenaiteFaculty of Medicine, Lund University, Lund, Sweden.
Mirjam J KnolCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Corneliu PopescuDr Victor Babes Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania.
Lenka SoučkováUniversity Hospital Brno, Brno, Czechia.
Marc SimonCentre Hospitalier de Luxembourg, Luxembourg.
Stella MichelakiNational Public Health Organisation (EODY), Athens, Greece.
Janine ReicheRobert Koch Institute, Berlin, Germany.
Annamária FerencziNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Concepción Delgado-SanzNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain.
Zvjezdana Lovrić MakarićCroatian Institute of Public Health, Zagreb, Croatia.
John Paul CauchiIDCU within Health promotion and disease prevention Directorate, G'mangia, Malta.
Cyril BarbezangeSciensano, Brussels, Belgium.
Els Van NederveldeUniversitair Ziekenhuis Brussel, Brussels, Belgium.
Joan O'DonnellHealth Service Executive-Health Protection Surveillance Centre, Dublin, Ireland.
Christine DurierInserm, US19, Villejuif, Paris, France.
Raquel GuiomarNational Institute of Health Dr Ricardo Jorge, Lisbon, Portugal.
Jesús CastillaInstituto de Salud Pública de Navarra-IdiSNA, Pamplona, Spain.
Indrė JonikaiteLithuanian University of Health Sciences, Kaunas, Lithuania.
Patricia Cjl Bruijning-VerhagenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Mihaela Lazar"Cantacuzino" National Military Medical Institute for Research-Development, Bucharest, Romania.
Regina DemlováFaculty of Medicine, Masaryk University, Brno, Czechia.
Gil WirtzCentre Hospitalier de Luxembourg, Luxembourg.
Marina AmeraliNational Public Health Organisation (EODY), Athens, Greece.
Ralf DürrwaldRobert Koch Institute, Berlin, Germany.
Mihály Pál KunstárNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Esther KisslingEpiconcept, Paris, France.
Sabrina BacciEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Marta ValencianoEpiconcept, Paris, France.
I-MOVE-COVID-19 hospital study teamThe members of these groups are listed under Collaborators.
VEBIS hospital study teamThe members of these groups are listed under Collaborators.
Members of the I-MOVE-COVID-19 and VEBIS hospital study teams (in addition to authors above)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionThe I-MOVE-COVID-19 and VEBIS hospital networks have been measuring COVID-19 vaccine effectiveness (VE) in participating European countries since early 2021.AimWe aimed to measure VE against PCR-confirmed SARS-CoV-2 in patients ≥ 20 years hospitalised with severe acute respiratory infection (SARI) from December 2021 to July 2022 (Omicron-dominant period).MethodsIn both networks, 46 hospitals (13 countries) follow a similar test-negative case-control protocol. We defined complete primary series vaccination (PSV) and first booster dose vaccination as last dose of either vaccine received ≥ 14 days before symptom onset (stratifying first booster into received < 150 and ≥ 150 days after last PSV dose). We measured VE overall, by vaccine category/product, age group and time since first mRNA booster dose, adjusting by site as a fixed effect, and by swab date, age, sex, and presence/absence of at least one commonly collected chronic condition.ResultsWe included 2,779 cases and 2,362 controls. The VE of all vaccine products combined against hospitalisation for laboratory-confirmed SARS-CoV-2 was 43% (95% CI: 29-54) for complete PSV (with last dose received ≥ 150 days before onset), while it was 59% (95% CI: 51-66) after addition of one booster dose. The VE was 85% (95% CI: 78-89), 70% (95% CI: 61-77) and 36% (95% CI: 17-51) for those with onset 14-59 days, 60-119 days and 120-179 days after booster vaccination, respectively.ConclusionsOur results suggest that, during the Omicron period, observed VE against SARI hospitalisation improved with first mRNA booster dose, particularly for those having symptom onset < 120 days after first booster dose.

Indexed as

COVID-19PneumoniaAdultCOVID-19 VaccinesEuropeHospitalizationHumansRNA, MessengerSARS-CoV-2Vaccine EfficacyCOVID-19 VaccinesRNA, MessengerCOVID-19EuropehospitalomicronSARS-CoV-2vaccine effectiveness

Identifiers

PMID37997665
PMCPMC10668256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.