Evidence map›Paper›PMID 37997011›Full record

ArticleMagnetic resonance in medicine2024

Changes in tissue sodium concentration and sodium relaxation times during the maturation of human knee cartilage: Ex vivo

Štefan Zbýň, Kai D Ludwig, Lauren E Watkins, Russell L Lagore, Amanda Nowacki, Ferenc Tóth, Marc A Tompkins, Lin Zhang, Gregor Adriany, Garry E Gold and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. A Sub-Microsecond Switch Enabling SWIFTMagnetic resonance in medicine · 2026
    Article
  2. Advances in cartilage imaging techniques.Nature reviews. Rheumatology · 2026
    Review
  3. European radiology experimental · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Štefan ZbýňCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-8211-2828
Kai D LudwigCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.
Lauren E WatkinsDepartment of Radiology, Department of Bioengineering, Stanford University, Palo Alto, California, USA.
Russell L LagoreCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.
Amanda NowackiCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.
Ferenc TóthDepartment of Veterinary Clinical Sciences, University of Minnesota, St. Paul, Minnesota, USA.ORCID 0000-0002-6615-389X
Marc A TompkinsDepartment of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota, USA.
Lin ZhangDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Gregor AdrianyCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-6428-9005
Garry E GoldDepartment of Radiology, Department of Bioengineering, Stanford University, Palo Alto, California, USA.ORCID 0000-0002-3207-822X
Kevin G SheaLucile Packard Children's Hospital, Stanford University School of Medicine, Palo Alto, California, USA.ORCID 0000-0002-4160-0163
Armin M NagelFriedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID 0000-0003-0948-1421
Cathy S CarlsonDepartment of Veterinary Clinical Sciences, University of Minnesota, St. Paul, Minnesota, USA.ORCID 0000-0002-0355-5525
Gregory J MetzgerCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-3187-6529
Jutta M EllermannCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-7109-9656
University of Minnesota · USPalo Alto University · USGerman Cancer Research Center · DELucile Packard Children's Hospital · US

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Musculoskeletal Training GrantT32AR050938 · NIAMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CLOHISY, DENIS R · 2004 to 2020
$3.0M
Computer Aided Diagnostic System for Prostate Cancer Detection Using Quantitative Multiparametric MRIR01CA241159 · NCI · UNIVERSITY OF MINNESOTA · PI METZGER, GREGORY JOHN · 2021 to 2025
$3.0M
Novel MRI Methods for Osteochondritis Dissecans (OCD) / Osteochondrosis (OC)R01AR070020 · NIAMS · UNIVERSITY OF MINNESOTA · PI CARLSON, CATHY S., ELLERMANN, JUTTA M · 2017 to 2021
$2.4M
NCI NIH HHS R01 CA241159NIAMS NIH HHS R01 AR070020NIAMS NIH HHS T32 AR050938NIBIB NIH HHS P41 EB027061
6 · The paper itself

Abstract

purposeTo evaluate the influence of skeletal maturation on sodium (

methodsTwelve pediatric knee specimens were imaged with whole-body 10.5 T MRI using a density-adapted 3D radial projection sequence to evaluate

resultsFrom birth to 12 years, cartilage water content decreased by 18%; collagen increased by 59%; and sGAG decreased by 36% (all R

conclusionTSC and relaxation parameters measured with

Indexed as

CartilageCartilage, ArticularChildChild, PreschoolCollagenHumansMagnetic Resonance ImagingSodiumWaterCollagenSodiumWater10.5 T23Na relaxation parametersbiochemical composition of cartilageknee cartilage maturationsodium (23Na) MRItissue sodium concentration

Identifiers

PMID37997011
PMCPMC10751033
OpenAlexW4388982294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.