ArticleNature aging2023
Clonally expanded memory CD8
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 30 citations in OpenAlex.
- T Cell Thoughts.Immunological reviews · 2026Review
- CD8Immunity & ageing : I & A · 2026Article
- Functional Heterogeneity of Immune Cell Subpopulations in Atherosclerosis: From Basic Mechanisms to Precision Therapy.Reviews in cardiovascular medicine · 2026Review
- Single-cell T-cell landscape in atherosclerosis: implications for targeted therapy and beyond.Journal of translational medicine · 2026Review
- Endothelial Elavl1 Is Required for CD8 T-Cell Persistence in Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Functional and Transcriptional Senescence Profiles of CD8+ T Cells Associate With the Presence of Carotid Plaques in People Living With HIV.The Journal of infectious diseases · 2026Article
- Perivascular adipose single-cell atlas identifies CD55Nature communications · 2026Article
- CD8Nature reviews. Cardiology · 2026Review
- T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age-Related Diseases.Immunological reviews · 2026Review
- Single-Cell Profiling of Splenic Immune Ageing and Chronic Stress Adaptations in Mice With Natural Microbiota.European journal of immunology · 2026Article
- Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs.Genome medicine · 2026Article
- High-Dimensional Single-Cell Analysis Reveals Coordinated Age-Dependent Neuroinflammatory Microglia-T cell Circuits in the Brain.bioRxiv : the preprint server for biology · 2025Article
- METTL3/RBM15 augments the stability of Kdm6b mRNA and promotes STAT1-mediated macrophage activation and atherosclerosis.Experimental & molecular medicine · 2025Article
- Mechanisms of Innate Immune Modulation by High-Fat Diet: Implications for Obesity and Asthma.Current allergy and asthma reports · 2025Review
- Immunological biomarkers and molecular signatures in healthy aging: early dynamics of subclinical atherosclerosis in a homogeneous elderly cohort.BMC cardiovascular disorders · 2025Article
- Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives.Cell reports. Medicine · 2025Review
- Inflammageing, a targetable pathway for preventing cardiovascular diseases.Cardiovascular research · 2025Review
- Atherogenic Risk in Shift Versus Non-Shift Workers: Associations with Sociodemographic and Lifestyle Factors.Diseases (Basel, Switzerland) · 2025Article
- CAFE: an integrated web app for high-dimensional analysis and visualization in spectral flow cytometry.Bioinformatics (Oxford, England) · 2025Article
- Metabolic and Immune Crosstalk in Cardiovascular Disease.Circulation research · 2025Review
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
14 authors at 2 institutions in 1 country.
Daniel J TyrrellDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. danieltyrrell@uabmc.edu.ORCID 0000-0002-0811-6724
Kathleen M WraggDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Judy ChenDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-5469-6619
Hui WangDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Jianrui SongDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Muriel G BlinDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Chase BoldingDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Donald VardamanDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kara GilesDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Harrison TidwellDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
Md Akkas AliDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-3626-3393
Abhinav JanappareddiDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Sherri C WoodDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Daniel R GoldsteinDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-6695-979X
University of Michigan · USUniversity of Alabama at Birmingham · US
Funding
XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THEODORE S LAWRENCE · 1988 to 2026
$178.2MXRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9MVirology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1MMechanisms to augment primary immunity in agingR01AG028082 · NIA · YALE UNIVERSITY · PI DENG, JANE C · 2007 to 2023
$6.9MNovel mechanisms of age-enhanced vasculopathy after heart transplantationR01AI138347 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDSTEIN, DANIEL ROBERT · 2018 to 2022
$2.7MRole of mitophagy in age-related respiratory and vascular diseasesR35HL155169 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDSTEIN, DANIEL ROBERT · 2021 to 2023
$1.8MNovel Inflammatory Pathway of Aged-Enhanced AtherosclerosisR01HL127687 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GOLDSTEIN, DANIEL ROBERT · 2016 to 2019
$1.6MCerebrovascular Mitochondrial Function in Aging and Ischemic InjuryR00AG068309 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TYRRELL, DANIEL · 2022 to 2024
$744kImmune Basis of how Inflammation, Atherosclerosis, and Aging Enhance Atrial FibrillationF32HL140728 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TYRRELL, DANIEL · 2018 to 2020
$165kCerebrovascular Mitochondrial Function in Aging and Ischemic InjuryK99AG068309 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TYRRELL, DANIEL · 2021 to 2022
$131kInterrogating the Effects of Aging on Influenza Infections: The Role of Prostaglandin E2F31HL158003 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHEN, JUDY · 2021 to 2023
$83kAmerican Heart Association-American Stroke Association 898210NCI NIH HHS P30 CA013148NCI NIH HHS P30 CA046592NHLBI NIH HHS F31 HL158003NHLBI NIH HHS F32 HL140728NHLBI NIH HHS R01 HL127687NHLBI NIH HHS R35 HL155169NIAID NIH HHS P30 AI027767NIAID NIH HHS R01 AI138347NIA NIH HHS K99 AG068309NIA NIH HHS R00 AG068309NIA NIH HHS R01 AG028082
Abstract
Aging is a strong risk factor for atherosclerosis and induces accumulation of memory CD8
Indexed as
AtherosclerosisPlaque, AtheroscleroticAgedAnimalsCD8-Positive T-LymphocytesHumansMemory T CellsMiceMice, Inbred C57BL
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.