Evidence map›Paper›PMID 37996678›Full record

ReviewResults and problems in cell differentiation2024

Syncytial Assembly Lines: Consequences of Multinucleate Cellular Compartments for Fungal Protein Synthesis.

Alex Mayer, Grace McLaughlin, Amy Gladfelter, N Louise Glass, Alexander Mela, Marcus Roper

Abstract readReview
PubMed Publisher
In one paragraph

Review in Results and problems in cell differentiation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alex MayerDepartment of Mathematics, University of California Los Angeles, Los Angeles, CA, USA.
Grace McLaughlinDepartment of Cell Biology, Duke University, Durham, NC, USA.
Amy GladfelterDepartment of Cell Biology, Duke University, Durham, NC, USA.
N Louise GlassDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA.
Alexander MelaDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA.
Marcus RoperDepartment of Mathematics, University of California Los Angeles, Los Angeles, CA, USA. mroper@math.ucla.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fast growth and prodigious cellular outputs make fungi powerful tools in biotechnology. Recent modeling work has exposed efficiency gains associated with dividing the labor of transcription over multiple nuclei, and experimental innovations are opening new windows on the capacities and adaptations that allow nuclei to behave autonomously or in coordination while sharing a single, common cytoplasm. Although the motivation of our review is to motivate and connect recent work toward a greater understanding of fungal factories, we use the analogy of the assembly line as an organizing idea for studying coordinated gene expression, generally.

Indexed as

Cell NucleusFungal ProteinsCytoplasmGiant CellsFungal ProteinsCompartmentalizationDivision of laborFilamentous fungiGene expressionMathematical modelNoiseNuclear autonomyNuclear coordinationSyncytia

Identifiers

PMID37996678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.