Evidence map›Paper›PMID 37996618›Full record

ArticleAnalytical and bioanalytical chemistry2024

Whole blood PT/aPTT assay based on non-contact drop-of-sample acoustic tweezing spectroscopy.

Nithya Kasireddy, Daishen Luo, Damir B Khismatullin

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nithya KasireddyDepartment of Biomedical Engineering and Tulane Institute for Integrative Engineering for Health and Medicine, Tulane University, 6823 St. Charles Avenue, 500 Lindy Boggs Center, New Orleans, LA, 70118, USA.
Daishen LuoDepartment of Biomedical Engineering and Tulane Institute for Integrative Engineering for Health and Medicine, Tulane University, 6823 St. Charles Avenue, 500 Lindy Boggs Center, New Orleans, LA, 70118, USA.
Damir B KhismatullinDepartment of Biomedical Engineering and Tulane Institute for Integrative Engineering for Health and Medicine, Tulane University, 6823 St. Charles Avenue, 500 Lindy Boggs Center, New Orleans, LA, 70118, USA. damir@tulane.edu.ORCID http://orcid.org/0000-0002-7533-8132
Tulane University · US

Funding

Drop-of-blood technology for home-use monitoring of anticoagulant therapyR43EB031013 · NIBIB · LEVISONICS, INC. · PI KASIREDDY, NITHYA · 2021 to 2021
$225k
NIH HHS EB031013
6 · The paper itself

Abstract

Most coagulation tests are photo-optical turbidimetric assays that require the removal of cellular components from whole blood for optical clearing. If the resulting blood plasma samples are hemolyzed, they may become unsuitable for turbidimetric analysis. To resolve this issue, whole-blood analogs to plasma turbidimetric assays need to be developed. Using samples collected from non-smokers (normal group), smokers (thrombotic group), and hemophilia A (bleeding group) patients, we demonstrate that the reaction time assessed from whole blood viscosity data of the drop-of-blood acoustic tweezing spectroscopy (ATS) technique strongly correlates (R

Indexed as

AcousticsFibrinogenBlood Coagulation TestsHumansPartial Thromboplastin TimeProthrombin TimeSpectrum AnalysisFibrinogenBlood viscosityCoagulation analysisFactor XIIIFibrinogenPartial thromboplastin timeProthrombin timeWhole blood

Identifiers

PMID37996618
OpenAlexW4388937095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.