Evidence map›Paper›PMID 37996543›Full record

ArticleAbdominal radiology (New York)2024

Endovascular management of sinistral portal hypertension-related variceal hemorrhage: a multicenter retrospective study.

Zhiquan Zhuang, Jingqin Ma, Zihan Zhang, Shuai Ju, Guoqiang Gu, Minjie Yang, Jiaze Yu, Zhiping Yan, Wen Zhang, Jianjun Luo

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhiquan Zhuang *Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Jingqin Ma *Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Zihan ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Shuai JuDepartment of Tumor Diagnosis and Therapy, Jinshan Hospital, Fudan University, Shanghai, 200540, China.
Guoqiang GuDepartment of Radiology, Minhang Hospital, Fudan University, Shanghai, 201100, China.
Minjie YangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Jiaze YuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Zhiping YanDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China.
Wen ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China. zhangwen2@zs-hospital.sh.cn.
Jianjun LuoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Fenglin Road, Xuhui District, Shanghai, 200032, No, China. luo.jianjun@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0003-4942-0439
Fudan University · CNJinshan Hospital of Fudan University · CN

Funding

Shanghai Clinical Research Center for Interventional Medicine 19MC1910300Shanghai Key Clinical Specialty Construction Program W2019028Zhongshan Hospital, Fudan University 2018ZSLC23
6 · The paper itself

Abstract

purposeThis study aimed to assess the safety and efficacy of endovascular managements, including splenic vein recanalization (SVR), partial splenic embolization (PSE), and percutaneous transsplenic gastric varices embolization combined with PSE (PSE+GVE), for management of SPH-related variceal hemorrhage (VH).

methodsA total of 61 patients with SPH-related VH from three hospitals were enrolled and classified into three groups: the SVR group (Group 1, n=24), the PSE+GVE group (Group 2, n=17), and the PSE group (Group 3, n=20). Baseline characteristics and clinical outcomes were compared among the groups.

resultsThe technical success rates for transhepatic and transsplenic SVR were 27.8% and 34.6%, respectively. No major complications were observed during any of the procedures. The median follow-up period was 53.2 months. The 2-year GI rebleeding rates for Group 1, 2, and 3 were 0%, 5.9%, and 35%, respectively. Groups 1 and 2 have a lower GI rebleeding rate (p = 0.002, p = 0.048, respectively) and better results of the degree of GV (p = 0.003, p = 0.044, respectively) compared to Group 3. No significant differences were found in 2-year GI rebleeding rates and the degree of GV between Group 1 and 2 (p = 0.415, p = 0.352, respectively).

conclusionSVR, PSE+GVE, and PSE seem safe and effective for management of SPH-related VH. SVR appears to be the superior treatment option. Transsplenic access may further increase the SVR success rate. PSE+GVE seems to have comparable outcomes in GV control and GI rebleeding rates compared to SVR, while superior to PSE.

Indexed as

Embolization, TherapeuticEndovascular ProceduresEsophageal and Gastric VaricesSinistral Portal HypertensionGastrointestinal HemorrhageHumansPortal VeinRetrospective StudiesTreatment OutcomePartial splenic embolizationSinistral portal hypertensionSplenic vein recanalizationTranssplenic accessVariceal bleeding

Identifiers

PMID37996543
OpenAlexW4388938813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.