Evidence map›Paper›PMID 37996478›Full record

ArticleScientific reports2023

A machine learning method to process voice samples for identification of Parkinson's disease.

Anu Iyer, Aaron Kemp, Yasir Rahmatallah, Lakshmi Pillai, Aliyah Glover, Fred Prior, Linda Larson-Prior, Tuhin Virmani

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Article
  3. Voice and Speech in Atypical Parkinsonian Disorders.Movement disorders clinical practice · 2026
    Review
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  6. Applications of Artificial Intelligence in Neurological Voice Disorders.World journal of otorhinolaryngology - head and neck surgery · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anu Iyer *Georgia Institute of Technology, Atlanta, 30332, USA.
Aaron Kemp *Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, 72205, USA. ASKemp@uams.edu.
Yasir RahmatallahBiomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
Lakshmi PillaiNeurology, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
Aliyah GloverNeurology, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
Fred PriorBiomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
Linda Larson-PriorBiomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
Tuhin VirmaniBiomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, 72205, USA.
University of Arkansas for Medical Sciences · USGeorgia Institute of Technology · US

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
NCATS NIH HHS UL1 TR003107NIH HHS UL1 TR003107
6 · The paper itself

Abstract

Machine learning approaches have been used for the automatic detection of Parkinson's disease with voice recordings being the most used data type due to the simple and non-invasive nature of acquiring such data. Although voice recordings captured via telephone or mobile devices allow much easier and wider access for data collection, current conflicting performance results limit their clinical applicability. This study has two novel contributions. First, we show the reliability of personal telephone-collected voice recordings of the sustained vowel /a/ in natural settings by collecting samples from 50 people with specialist-diagnosed Parkinson's disease and 50 healthy controls and applying machine learning classification with voice features related to phonation. Second, we utilize a novel application of a pre-trained convolutional neural network (Inception V3) with transfer learning to analyze the spectrograms of the sustained vowel from these samples. This approach considers speech intensity estimates across time and frequency scales rather than collapsing measurements across time. We show the superiority of our deep learning model for the task of classifying people with Parkinson's disease as distinct from healthy controls.

Indexed as

Parkinson DiseaseVoiceHumansMachine LearningPhonationReproducibility of Results

Identifiers

PMID37996478
PMCPMC10667335
OpenAlexW4388938846

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.