Evidence map›Paper›PMID 37996339›Full record

ArticleThe Lancet. Digital health2024

Operational greenhouse-gas emissions of deep learning in digital pathology: a modelling study.

Alireza Vafaei Sadr, Roman Bülow, Saskia von Stillfried, Nikolas E J Schmitz, Pourya Pilva, David L Hölscher, Peiman Pilehchi Ha, Marcel Schweiker, Peter Boor

Abstract read
In one paragraph

Article in The Lancet. Digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  6. Decoding pathology: the role of computational pathology in research and diagnostics.Pflugers Archiv : European journal of physiology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Deep learning applications in digital pathology.Nature reviews. Nephrology · 2024
    Article
  12. [Artificial intelligence in kidney transplant pathology].Pathologie (Heidelberg, Germany) · 2024
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Alireza Vafaei SadrInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany; Department of Public Health Sciences, College of Medicine, Pennsylvania State University, Hershey, PA, USA.
Roman BülowInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Saskia von StillfriedInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Nikolas E J SchmitzInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Pourya PilvaInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
David L HölscherInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Peiman Pilehchi HaHealthy Living Spaces Lab, Institute for Occupational, Social and Environmental Medicine, Medical Faculty, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Marcel SchweikerHealthy Living Spaces Lab, Institute for Occupational, Social and Environmental Medicine, Medical Faculty, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.
Peter BoorInstitute of Pathology, University Hospital Aachen, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany; Department of Nephrology and Immunology, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany. Electronic address: pboor@ukaachen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep learning is a promising way to improve health care. Image-processing medical disciplines, such as pathology, are expected to be transformed by deep learning. The first clinically applicable deep-learning diagnostic support tools are already available in cancer pathology, and their number is increasing. However, data on the environmental sustainability of these tools are scarce. We aimed to conduct an environmental-sustainability analysis of a theoretical implementation of deep learning in patient-care pathology.

methodsFor this modelling study, we first assembled and calculated relevant data and parameters of a digital-pathology workflow. Data were breast and prostate specimens from the university clinic at the Institute of Pathology of the Rheinisch-Westfälische Technische Hochschule Aachen (Aachen, Germany), for which commercially available deep learning was already available. Only specimens collected between Jan 1 and Dec 31, 2019 were used, to omit potential biases due to the COVID-19 pandemic. Our final selection was based on 2 representative weeks outside holidays, covering different types of specimens. To calculate carbon dioxide (CO

findingsThe pathology database contained 35 552 specimens (237 179 slides), 6420 of which were prostate specimens (10 115 slides) and 11 801 of which were breast specimens (19 763 slides). We selected and subsequently digitised 140 slides from eight breast-cancer cases and 223 slides from five prostate-cancer cases. Applying large deep-learning models on all WSI tiles of prostate and breast pathology cases would result in yearly CO

interpretationOur findings suggest that widespread use of deep learning in pathology might have considerable global-warming potential. The medical community, policy decision makers, and the public should be aware of this potential and encourage the use of CO

fundingGerman Research Foundation, European Research Council, German Federal Ministry of Education and Research, Health, Economic Affairs and Climate Action, and the Innovation Fund of the Federal Joint Committee.

Indexed as

Deep LearningGreenhouse GasesNeoplasmsCarbon DioxideHumansPandemicsCarbon DioxideGreenhouse Gases

Identifiers

PMID37996339
PMCPMC10728828

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.