Evidence map›Paper›PMID 37995843›Full record

ArticleJournal of biomedical informatics2023

Fair patient model: Mitigating bias in the patient representation learned from the electronic health records.

Sonish Sivarajkumar, Yufei Huang, Yanshan Wang

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sonish SivarajkumarIntelligent Systems Program, School of Computing and Information, University of Pittsburgh, Pittsburgh, PA, United States.
Yufei HuangIntelligent Systems Program, School of Computing and Information, University of Pittsburgh, Pittsburgh, PA, United States; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Department of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA, United States; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA, United States.
Yanshan WangIntelligent Systems Program, School of Computing and Information, University of Pittsburgh, Pittsburgh, PA, United States; Department of Health Information Management, University of Pittsburgh, Pittsburgh, PA, United States; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, United States; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, United States; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA, United States. Electronic address: yanshan.wang@pitt.edu.
University of Pittsburgh · US

Funding

ENACT: Translating Health Informatics Tools to Research and Clinical Decision MakingU24TR004111 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEVEN E REIS, SHYAM VISWESWARAN · 2022 to 2026
$23.3M
Closing the loop with an automatic referral population and summarization systemR01LM014306 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI Yifan Peng, Justin Frederick Rousseau · 2023 to 2026
$2.7M
NCATS NIH HHS U24 TR004111NLM NIH HHS R01 LM014306
6 · The paper itself

Abstract

objectiveTo pre-train fair and unbiased patient representations from Electronic Health Records (EHRs) using a novel weighted loss function that reduces bias and improves fairness in deep representation learning models.

methodsWe defined a new loss function, called weighted loss function, in the deep representation learning model to balance the importance of different groups of patients and features. We applied the proposed model, called Fair Patient Model (FPM), to a sample of 34,739 patients from the MIMIC-III dataset and learned patient representations for four clinical outcome prediction tasks.

resultsFPM outperformed the baseline models in terms of three fairness metrics: demographic parity, equality of opportunity difference, and equalized odds ratio. FPM also achieved comparable predictive performance with the baselines, with an average accuracy of 0.7912. Feature analysis revealed that FPM captured more information from clinical features than the baselines.

conclusionFPM is a novel method to pre-train fair and unbiased patient representations from the EHR data using a weighted loss function. The learned representations can be used for various downstream tasks in healthcare and can be extended to other domains where fairness is important.

Indexed as

BenchmarkingElectronic Health RecordsHumansPrognosis

Identifiers

PMID37995843
PMCPMC10850918
OpenAlexW4388906294

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.