ArticleCell reports2023
Development of white matter fiber covariance networks supports executive function in youth.
Abstract read
In one paragraph
Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- White matter integrity buffers the impact of screen time on inhibitory control in youth.Developmental cognitive neuroscience · 2026Article
- Mapping the spatiotemporal continuum of structural connectivity development across the human connectome in youth.Nature communications · 2026Article
- Effects of neighborhood level health and environment quality on academic and executive abilities in youth with Noonan syndrome spectrum disorder.Journal of the International Neuropsychological Society : JINS · 2026Article
- Annual Research Review: Neural mechanisms of eating disorders in youth - from current theory and findings to future directions.Journal of child psychology and psychiatry, and allied disciplines · 2026Review
- Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology.Nature communications · 2026Article
- Hierarchical maturation of structural brain connectomes from birth to childhood.Nature communications · 2026Article
- Taming dimensionality in big neuroimaging data: Efficient orthonormal projective NMF via stochastic learning and data compression.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Rate of brain aging associates with future executive function in Asian children and older adults.eLife · 2025Article
- Mapping the white-matter functional connectome: a personal perspective.Psychoradiology · 2025Review
- Morphometric brain organization across the human lifespan reveals increased dispersion linked to cognitive performance.PLoS biology · 2024Article
- Accelerated maturation of brain circuits and executive function in adolescents who experienced the COVID-19 pandemic.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
- Commented on by
- Update of
Authors and funding
20 authors.
Joëlle BagautdinovaPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Josiane BourquePenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Valerie J SydnorPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Matthew CieslakPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Aaron F Alexander-BlochDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Maxwell A BertoleroPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Philip A CookDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Raquel E GurDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ruben C GurDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Fengling HuDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Bart LarsenPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Tyler M MooreDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Hamsanandini RadhakrishnanPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
David R RoalfDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Russel T ShinoharaDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Tinashe M TaperaPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA.
Chenying ZhaoPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA.
Aristeidis SotirasDepartment of Radiology and Institute for Informatics, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63130, USA.
Christos DavatzikosDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Theodore D SatterthwaitePenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Lifespan Brain Institute (LiBI) of Penn Medicine and Children's Hospital of Philadelphia (CHOP), University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: sattertt@pennmedicine.upenn.edu.
Funding
Longitudinal Mapping of Network Development Underlying Executive Dysfunction in AdolescenceR01MH113550 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Danielle Smith Bassett, Theodore Satterthwaite · 2018 to 2026
$6.9MPersonalized Functional Network Modeling to Characterize and Predict Psychopathology in YouthR01EB022573 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Yong Fan, Theodore Satterthwaite · 2016 to 2026
$6.0MInter-modal Coupling Image AnalyticsR01MH112847 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Theodore Satterthwaite, Russell Takeshi Shinohara · 2017 to 2026
$5.9MPrecision mapping of individualized executive networks in youthR37MH125829 · NIMH · UNIVERSITY OF MINNESOTA · PI Damien A Fair, Theodore Satterthwaite · 2021 to 2026
$4.7MThe Genetics of Personalized Functional MRI NetworksR01MH132934 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$4.2MHarmonization of Multi-Site Neuroimaging Data from Complex Study DesignsR01MH123550 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2020 to 2025
$4.0MUltra-high field GluCEST MRI and MRS in youth at risk for psychosisR01MH120174 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2020 to 2024
$3.8MEvolution of Psychosis in Youth: Multimodal Risk and Resilience MarkersR01MH119219 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E, GUR, RUBEN C. · 2019 to 2023
$3.8MThe Neuroimaging Brain Chart Software SuiteU24NS130411 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Christos Davatzikos, Yong Fan · 2023 to 2026
$3.7MOlfactory and facial markers of developmental risk for psychosis in 22q11 deletion syndromeR01MH119185 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2019 to 2024
$3.5MReproducible imaging-based brain growth charts for psychiatryR01MH120482 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI MILHAM, MICHAEL PETER, SATTERTHWAITE, THEODORE · 2019 to 2023
$3.5MPrecision brain charts for imaging-genomics of schizophrenia and the psychosis spectrumR01MH133843 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$3.2MNIA NIH HHS R01 AG067103NIBIB NIH HHS R01 EB022573NIMH NIH HHS K08 MH120564NIMH NIH HHS K99 MH127293NIMH NIH HHS R00 MH127293NIMH NIH HHS R01 MH112847NIMH NIH HHS R01 MH113550NIMH NIH HHS R01 MH119185NIMH NIH HHS R01 MH119219NIMH NIH HHS R01 MH120174NIMH NIH HHS R01 MH120482NIMH NIH HHS R01 MH123550NIMH NIH HHS R01 MH132934NIMH NIH HHS R01 MH133843NIMH NIH HHS R37 MH125829NIMH NIH HHS RF1 MH116920NIMH NIH HHS RF1 MH121867NINDS NIH HHS U24 NS130411
Abstract
During adolescence, the brain undergoes extensive changes in white matter structure that support cognition. Data-driven approaches applied to cortical surface properties have led the field to understand brain development as a spatially and temporally coordinated mechanism that follows hierarchically organized gradients of change. Although white matter development also appears asynchronous, previous studies have relied largely on anatomical tract-based atlases, precluding a direct assessment of how white matter structure is spatially and temporally coordinated. Harnessing advances in diffusion modeling and machine learning, we identified 14 data-driven patterns of covarying white matter structure in a large sample of youth. Fiber covariance networks aligned with known major tracts, while also capturing distinct patterns of spatial covariance across distributed white matter locations. Most networks showed age-related increases in fiber network properties, which were also related to developmental changes in executive function. This study delineates data-driven patterns of white matter development that support cognition.
Indexed as
White MatterAdolescentBrainCognitionExecutive FunctionHumansCP: Neurosciencedevelopmentdiffusion-weighted imagingexecutive functionfixel-based analysisnetworknon-negative matrix factorizationyouth
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.