Evidence map›Paper›PMID 37994997›Full record

ArticleObesity surgery2024

The Degree of Preoperative Hypoalbuminemia Is Associated with Risk of Postoperative Complications in Metabolic and Bariatric Surgery Patients.

Lee D Ying, Grace F Chao, Joseph Canner, Elena Graetz, Saber Ghiassi, Jennifer S Schwartz, Emily J Zolfaghari, Eric B Schneider, Karen E Gibbs

Abstract read
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In one paragraph

Article in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Low-energy diets before metabolic bariatric surgery: A systematic review of the effect on total body weight, liver volume, glycemia and side effects.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lee D YingDepartment of Surgery, Yale New Haven Hospital, New Haven, CT, USA. Lee.Ying@yale.edu.ORCID 0000-0001-7638-1960
Grace F ChaoYale School of Medicine, New Haven, CT, USA.
Joseph CannerYale School of Medicine, New Haven, CT, USA.
Elena GraetzYale School of Medicine, New Haven, CT, USA.
Saber GhiassiYale School of Medicine, New Haven, CT, USA.
Jennifer S SchwartzYale School of Medicine, New Haven, CT, USA.
Emily J ZolfaghariDepartment of Surgery, Yale New Haven Hospital, New Haven, CT, USA.
Eric B SchneiderYale School of Medicine, New Haven, CT, USA.
Karen E GibbsYale School of Medicine, New Haven, CT, USA.
Yale University · USYale New Haven Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence and impact of hypoalbuminemia in bariatric surgery patients is poorly characterized. We describe its distribution in laparoscopic sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) patients undergoing primary or revision surgeries and assess its impact on postoperative complications.

methodsThe Metabolic and Bariatric Surgery Quality Improvement Program Database (2015 to 2021) was analyzed. Hypoalbuminemia was defined as Severe (< 3 g/dL), Moderate (3 ≤ 3.5 g/dL), Mild (3.5 ≤ 4 g/dL), or Normal (≥ 4 g/dL). Multivariable logistic regression was performed to calculate odds ratios of postoperative complications compared to those with Normal albumin after controlling for procedure, age, gender, race, body mass index, functional status, American Society of Anesthesia class, and operative length.

resultsA total of 817,310 patients undergoing Primary surgery and 69,938 patients undergoing Revision/Conversion ("Revision") surgery were analyzed. The prevalence of hypoalbuminemia was as follows (Primary, Revision): Severe, 0.3%, 0.6%; Moderate, 5.2%, 6.5%; Mild, 28.3%, 31.4%; Normal, 66.2%, 61.4%. Primary and Revision patients with hypoalbuminemia had a significantly higher prevalence (p < 0.01) of several co-morbidities, including hypertension and insulin-dependent diabetes. Any degree of hypoalbuminemia increased the odds ratio of several complications in Primary and Revision patients, including readmission, intervention, and reoperation. In Primary patients, all levels of hypoalbuminemia also increased the odds ratio of unplanned intubation, intensive care unit admission, and venous thromboembolism requiring therapy.

conclusionOver 30% of patients present with hypoalbuminemia. Even mild hypoalbuminemia was associated with an increased rate of several complications including readmission, intervention, and reoperation. Ensuring nutritional optimization, especially prior to revision surgery, may improve outcomes in this challenging population.

Indexed as

Bariatric SurgeryGastric BypassHypoalbuminemiaObesity, MorbidGastrectomyHumansPostoperative ComplicationsRetrospective StudiesTreatment OutcomeHypoalbuminemiaPostoperative riskPrehabilitation

Identifiers

PMID37994997
OpenAlexW4388940103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.